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Titolo:
CLINICAL-SIGNIFICANCE OF ECHOCONTRAST ENHANCEMENT IN NEUROSONOLOGY - AIM OF THE STUDY
Autore:
NABAVI DG; DROSTE DW; SCHULTEALTEDORNEBURG G; KEMENY V; PANZICA M; WEBER S; RINGELSTEIN EB;
Indirizzi:
UNIV MUNSTER,NEUROL KLIN & POLIKLIN,ALBERT SCHWEITZER STR 33 D-48129 MUNSTER GERMANY SCHERING DEUTSCHLAND GMBH BERLIN GERMANY
Titolo Testata:
Fortschritte der Neurologie, Psychiatrie
fascicolo: 10, volume: 66, anno: 1998,
pagine: 466 - 473
SICI:
0720-4299(1998)66:10<466:COEEIN>2.0.ZU;2-A
Fonte:
ISI
Lingua:
GER
Soggetto:
POWER DOPPLER; COLOR DOPPLER; CONTRAST-MEDIUM; CAROTID-ARTERY; SONOGRAPHY; ULTRASOUND; PHASE-2;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
21
Recensione:
Indirizzi per estratti:
Citazione:
D.G. Nabavi et al., "CLINICAL-SIGNIFICANCE OF ECHOCONTRAST ENHANCEMENT IN NEUROSONOLOGY - AIM OF THE STUDY", Fortschritte der Neurologie, Psychiatrie, 66(10), 1998, pp. 466-473

Abstract

To evaluate the potential and limitations of echocontrast enhancementusing Levovist(R) in a non selected consecutive cohort of neurological patients with insufficient native ultrasound investigations. Methods: In 91 patients an indication for echocontrast application was seen after an insufficient extracranial (n =17), transtemporal (n = 54), andtransforaminal (n = 20) Doppler- und color-coded Duplex sonography. Levovist(R) was injected at a concentration of 400 mg/ml and 200-400 mg/ml for the transcranial and extracranial approach, respectively. The effect of the echocontrast enhancement was assessed semiquantitativelywith respect to signal enhancement, imaging quality, and diagnostic confidence. Results: In a total of 83 patients (91%) the signal enhancement led to a moderate to high imaging quality allowing to reach 67 definite neurovascular diagnoses (74%). In subgroup analysis, the amountof sufficiently confident examinations was significantly higher for the transtemporal and transforaminal (both 80%) than for the extracranial approach (47%). The latter was mostly due to artificial signals derived from adjacent neck vessels. Conclusion: Levovist(R) constitutes asafe and highly effective diagnostic tool especially for the transtemporal and transforaminal neurosonographical imaging. By means of a differentiated application of echocontrast agents, its cost-effectivenesscan be increased and the need for other potential invasive and expansive neuroimaging methods can be further reduced.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 17/01/21 alle ore 18:15:03