Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
SIGNIFICANCE OF IGA ANTIPHOSPHOLIPID ANTIBODIES
Autore:
WILSON WA; FAGHIRI Z; TAHERI F; GHARAVI AE;
Indirizzi:
LOUISIANA STATE UNIV,MED CTR,DEPT MED,RHEUMATOL SECT,1542 TULANE AVE NEW ORLEANS LA 70112 MOREHOUSE SCH MED ATLANTA GA 30310 SHIRAZ UNIV MED SCI SHIRAZ IRAN
Titolo Testata:
Lupus
, volume: 7, anno: 1998, supplemento:, 2
pagine: 110 - 113
SICI:
0961-2033(1998)7:<110:SOIAA>2.0.ZU;2-K
Fonte:
ISI
Lingua:
ENG
Soggetto:
SYSTEMIC LUPUS-ERYTHEMATOSUS; ANTI-CARDIOLIPIN ANTIBODIES; LYMPHOCYTE-T ALVEOLITIS; I-ASSOCIATED MYELOPATHY; VIRUS TYPE-I; ANTICARDIOLIPIN ANTIBODIES; CLINICAL-SIGNIFICANCE; ISOTYPE DISTRIBUTION; IMMUNOGLOBULIN-A; APOLIPOPROTEIN-H;
Keywords:
IGA ANTICARDIOLIPIN; IGA ANTI-BETA(2)GLYCOPROTEIN; SLE; HAM-TSP; HTLV-1;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
34
Recensione:
Indirizzi per estratti:
Citazione:
W.A. Wilson et al., "SIGNIFICANCE OF IGA ANTIPHOSPHOLIPID ANTIBODIES", Lupus, 7, 1998, pp. 110-113

Abstract

IgA anticardiolipin (IgA aCL) and IgA anti beta(2)-glycoprotein-I(IgAanti beta(2)GP1) antibodies are common in SLE and have been associated in some studies with thromboses and thrombocytopenia. Experimental work suggests that IgA aCL are as prothrombotic as the IgG-IgM isotypes. However, in SLE there appears to be less concordance between IgA aCland IgA anti beta(2)GP1 as compared with the concordance between IgG and IgM isotypes, suggesting significant differences in their origins and specificities. For example, there may be a greater mucosal contribution to production of IgA anti beta(2)GP1 than IgA aCL. Infections may have a greater role in the presence of IgA aCL than IgA anti beta(2)GP1 antibodies.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/09/20 alle ore 07:37:51