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Titolo:
ODORANT-INDUCED AND SNIFF-INDUCED ACTIVATION IN THE CEREBELLUM OF THEHUMAN
Autore:
SOBEL N; PRABHAKARAN V; HARTLEY CA; DESMOND JE; ZHAO Z; GLOVER GH; GABRIELI JDE; SULLIVAN EV;
Indirizzi:
STANFORD UNIV,PROGRAM NEUROSCI,JORDAN HALL BLDG 420 STANFORD CA 94305 STANFORD UNIV,PROGRAM SYMBOL SYST STANFORD CA 94305 STANFORD UNIV,DEPT PSYCHOL STANFORD CA 94305 STANFORD UNIV,DEPT RADIOL STANFORD CA 94305 STANFORD UNIV,DEPT PSYCHIAT & BEHAV SCI STANFORD CA 94305
Titolo Testata:
The Journal of neuroscience
fascicolo: 21, volume: 18, anno: 1998,
pagine: 8990 - 9001
SICI:
0270-6474(1998)18:21<8990:OASAIT>2.0.ZU;2-J
Fonte:
ISI
Lingua:
ENG
Soggetto:
ANATOMIC-MR CORRELATION; VENTRAL TEGMENTAL AREA; VESTIBULOOCULAR REFLEX; FUNCTIONAL MRI; OLFACTORY DYSFUNCTION; COGNITIVE FUNCTIONS; MULTIPLE-SCLEROSIS; SAGITTAL PLANE; NEURAL BASIS; MOTOR;
Keywords:
OLFACTION; CEREBELLUM; SNIFFING; ODOR; SMELL; HUMAN;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
88
Recensione:
Indirizzi per estratti:
Citazione:
N. Sobel et al., "ODORANT-INDUCED AND SNIFF-INDUCED ACTIVATION IN THE CEREBELLUM OF THEHUMAN", The Journal of neuroscience, 18(21), 1998, pp. 8990-9001

Abstract

Functional magnetic resonance imaging was used to test whether odorants induce activation in the cerebellum of the human. The odorants vanillin and propionic acid both induced significant activation, primarilyin the posterior lateral hemispheres. Activation was concentration-dependent, greater after stimulation with higher concentration odorants. By contrast, the action of sniffing nonodorized air induced significant activation in the anterior cerebellum, primarily in the central lobule. These findings demonstrate that the cerebellum plays a role in human olfaction. A hypothesis is proposed whereby the cerebellum maintains a feedback mechanism that regulates sniff volume in relation to odor concentration.

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Documento generato il 19/01/20 alle ore 20:30:39