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Titolo:
DETERMINATION OF SYNTHETIC HYDROXYTYROSOL IN RAT PLASMA BY GC-MS
Autore:
BAI C; YAN XJ; TAKENAKA M; SEKIYA K; NAGATA T;
Indirizzi:
MINIST AGR FORESTRY & FISHERIES,NATL FOOD RES INST,2-1-2 KANNONDAI IBARAKI OSAKA 3058642 JAPAN MINIST AGR FORESTRY & FISHERIES,NATL FOOD RES INST IBARAKI OSAKA 3058642 JAPAN SHIKOKU NATL AGR EXPT STN KAGAWA 765 JAPAN
Titolo Testata:
Journal of agricultural and food chemistry
fascicolo: 10, volume: 46, anno: 1998,
pagine: 3998 - 4001
SICI:
0021-8561(1998)46:10<3998:DOSHIR>2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Soggetto:
LOW-DENSITY-LIPOPROTEIN; VIRGIN OLIVE OIL; PLATELET-AGGREGATION; PHENOLIC-COMPOUNDS; INHIBITION; OXIDATION;
Keywords:
HYDROXYTYROSOL; DIHYDROXYPHENYLETHANOL (DPE); PLASMA; GC-MS; METABOLISM;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
17
Recensione:
Indirizzi per estratti:
Citazione:
C. Bai et al., "DETERMINATION OF SYNTHETIC HYDROXYTYROSOL IN RAT PLASMA BY GC-MS", Journal of agricultural and food chemistry, 46(10), 1998, pp. 3998-4001

Abstract

2-(3,4-Dihydroxyphenyl)ethanol (DPE), the major phenolic compound in olive oil, may contribute the antioxidative activities and other beneficial effects to olive oil. However, the lack of commercial available DPE and procedures sensitive enough to quantitatively determine DPE inbody fluids have limited the bioavailability and metabolism studies on this phenolic compound. In the present study, DPE was synthesized with high yield and high purity and administered orally to rats. DPE concentration in rat plasma, after absorption, was measured using a sensitive GC-MS-SIM method. The results indicated that the highest level ofDPE in plasma was detected at 5-10 min after administration. During this period, the concentration of DPE fluctuated widely with the individual.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/12/20 alle ore 01:36:40