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Titolo:
HEPATOCELLULAR-CARCINOMA TREATMENT WITH PERCUTANEOUS ETHANOL INJECTION - EVALUATION WITH CONTRAST-ENHANCED COLOR DOPPLER US
Autore:
BARTOLOZZI C; LENCIONI R; RICCI P; PAOLICCHI A; ROSSI P; PASSARIELLO R;
Indirizzi:
UNIV PISA,DEPT ONCOL,DIV DIAGNOST & INTERVENT RADIOL,VIA ROMA 67 I-56125 PISA ITALY UNIV PISA,DEPT ONCOL,DIV DIAGNOST & INTERVENT RADIOL I-56125 PISA ITALY UNIV ROMA LA SAPIENZA,DEPT RADIOL ROME ITALY
Titolo Testata:
Radiology
fascicolo: 2, volume: 209, anno: 1998,
pagine: 387 - 393
SICI:
0033-8419(1998)209:2<387:HTWPEI>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
MALIGNANT HEPATIC-TUMORS; ABLATION THERAPY; CIRRHOSIS; CT; LIVER; AGENT;
Keywords:
ALCOHOL; LIVER, INTERVENTIONAL PROCEDURE; LIVER NEOPLASMS; LIVER NEOPLASMS, CT; LIVER NEOPLASMS, US; ULTRASOUND (US), CONTRAST MEDIA; ULTRASOUND (US), DOPPLER STUDIES;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
20
Recensione:
Indirizzi per estratti:
Citazione:
C. Bartolozzi et al., "HEPATOCELLULAR-CARCINOMA TREATMENT WITH PERCUTANEOUS ETHANOL INJECTION - EVALUATION WITH CONTRAST-ENHANCED COLOR DOPPLER US", Radiology, 209(2), 1998, pp. 387-393

Abstract

PURPOSE: To investigate the ability of contrast agent-enhanced color Doppler ultrasonography (US) in evaluating the response of hepatocellular carcinoma (HCC) to percutaneous ethanol injection (PEI). MATERIALSAND METHODS: Forty-two patients (36 men, six women; age range, 51-79 years) with 54 1.3-7.0-cm-diameter (mean +/- SD, 2.8 cm +/- 1.1) HCC lesions were examined with contrast-enhanced color,Doppler US before and after PEI. Spiral computed tomography (CT) and percutaneous biopsy also were performed to establish the outcome of therapy. RESULTS: Before PEI, intratumoral color signals were demonstrated at contrast-enhanced color Doppler US in 47 (87%) lesions (in 40 patients). After PEI, blood flow signals were no longer detected in all 34 of the lesions that were found to be necrotic at spiral CT and biopsy. In 12 (92%) of 13lesions containing residual viable tumor, intratumoral color signals corresponding to the enhancing areas at spiral CT were still identified at contrast-enhanced color Doppler US. These 12 lesions were retreated with PEI by targeting the areas of residual tumor with contrast-enhanced color Doppler US guidance. Complete necrosis was seen after the second PEI cycle in nine of 12 lesions. CONCLUSION: Contrast-enhanced color Doppler US shows promise in assessing the therapeutic effect of PEI on HCC and in guiding additional treatment in cases of incomplete response.

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Documento generato il 04/07/20 alle ore 12:10:27