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Titolo:
A THEORETICAL-STUDY OF THE EFFECT OF EXPERIMENTAL NOISE ON THE MEASUREMENT OF ANISOTROPY IN-DIFFUSION IMAGING
Autore:
BASTIN ME; ARMITAGE PA; MARSHALL I;
Indirizzi:
UNIV EDINBURGH,WESTERN GEN HOSP,DEPT MED PHYS & MED ENGN,CREWE RD EDINBURGH EH4 2XU MIDLOTHIAN SCOTLAND
Titolo Testata:
Magnetic resonance imaging
fascicolo: 7, volume: 16, anno: 1998,
pagine: 773 - 785
SICI:
0730-725X(1998)16:7<773:ATOTEO>2.0.ZU;2-C
Fonte:
ISI
Lingua:
ENG
Soggetto:
HUMAN BRAIN; MAGNETIC-RESONANCE; WATER DIFFUSION; SELF-DIFFUSION; COEFFICIENT; SPECTROSCOPY; ARTIFACTS; IMAGES; TENSOR; STROKE;
Keywords:
MONTE CARLO SIMULATIONS; DIFFUSION TENSOR IMAGING; DIFFUSION WEIGHTED IMAGING; EXPERIMENTAL NOISE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
29
Recensione:
Indirizzi per estratti:
Citazione:
M.E. Bastin et al., "A THEORETICAL-STUDY OF THE EFFECT OF EXPERIMENTAL NOISE ON THE MEASUREMENT OF ANISOTROPY IN-DIFFUSION IMAGING", Magnetic resonance imaging, 16(7), 1998, pp. 773-785

Abstract

Diffusion tensor imaging (DTT) is a modality known to be highly sensitive to the detrimental effects of experimental noise. Here, using Monte Carlo simulations, we compare and contrast how noise complicates the measurement of diffusion anisotropy in diffusion tensor and conventional diffusion-weighted imaging (DWI). As the signal-to-noise ratio (SNR) decreases below a value of approximately 20, the eigenvalues (lambda(i)) of the diffusion tensor D are found to diverge rapidly from their true values, with the result that the measured anisotropy can be significantly in error and isotropic structures falsely assigned a high level of anisotropy, The effect of noise on the rotationally variant indices, calculated from a conventional diffusion-weighted imaging experiment, is found to be much less insidious, because the apparent diffusion coefficients (ADCs) diverge only slowly as the signal-to-noise decreases. Thus, although rotationally variant indices almost always underestimate the true diffusion anisotropy, they show only a small susceptibility to experimental noise and hence, are preferred to their rotationally invariant counterparts when the signal-to-noise ratio is small. (C) 1998 Elsevier Science Inc.

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Documento generato il 02/07/20 alle ore 19:07:00