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Titolo:
ABNORMAL FUNCTIONAL CONNECTIVITY IN ALZHEIMERS-DISEASE - INTRAHEMISPHERIC EEG COHERENCE DURING REST AND PHOTIC-STIMULATION
Autore:
WADA Y; NANBU Y; KIKUCHI M; KOSHINO Y; HASHIMOTO T; YAMAGUCHI N;
Indirizzi:
KANAZAWA UNIV,SCH MED,DEPT NEUROPSYCHIAT,13-1 TAKARA MACHI KANAZAWA ISHIKAWA 920864 JAPAN KANAZAWA UNIV HOSP,DEPT CENT CLIN LAB KANAZAWA ISHIKAWA 920864 JAPAN MATSUBARA HOSP KANAZAWA ISHIKAWA 920093 JAPAN
Titolo Testata:
European archives of psychiatry and clinical neuroscience
fascicolo: 4, volume: 248, anno: 1998,
pagine: 203 - 208
SICI:
0940-1334(1998)248:4<203:AFCIA->2.0.ZU;2-0
Fonte:
ISI
Lingua:
ENG
Soggetto:
VISUAL EVOKED-POTENTIALS; CHOLINERGIC NEURONS; SENILE DEMENTIA; SELECTIVE LOSS; CORTEX; TASK; SCHIZOPHRENIA; DISTURBANCES; DIAGNOSIS; POWER;
Keywords:
ALZHEIMERS DISEASE; COHERENCE ANALYSIS; PHOTIC STIMULATION; EEG; FUNCTIONAL CONNECTIVITY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
49
Recensione:
Indirizzi per estratti:
Citazione:
Y. Wada et al., "ABNORMAL FUNCTIONAL CONNECTIVITY IN ALZHEIMERS-DISEASE - INTRAHEMISPHERIC EEG COHERENCE DURING REST AND PHOTIC-STIMULATION", European archives of psychiatry and clinical neuroscience, 248(4), 1998, pp. 203-208

Abstract

Electroencephalography (EEG) coherence provides a measure of functional correlations between two EEG signals. The present study was conducted to examine intrahemispheric EEG coherence at rest and during photicstimulation (PS; 5, 10 and 15 Hz) in ten unmedicated patients with presenile dementia of the Alzheimer type (AD; mean age at onset 56 years). In the resting EEG, the AD patients had significantly lower coherence than gender- and age-matched control subjects in the alpha-1, alpha-2 and beta-1 frequency bands. The EEG analysis during PS also showed that the patients had significantly lower coherence in the frequency corresponding to PS at 10 and 15 Hz. In this study, the changes in coherence from the resting state to the stimulus condition (i.e. PS-related coherence reactivity) were examined. The patients were found to showsignificantly smaller coherence reactivity to PS at 5 and 15 Hz. These findings suggest that, in addition to the resting state, AD patientshave an impairment of intrahemispheric functional connectivity duringPS. They also suggest that AD shows a failure of PS-related functional reorganization.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/04/20 alle ore 19:28:26