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Titolo:
EVALUATION OF THE BACTEC RADIOMETRIC METHOD IN THE EARLY DIAGNOSIS OFTUBERCULOSIS
Autore:
VENKATARAMAN P; HERBERT D; PARAMASIVAN CN;
Indirizzi:
TB RES CTR,MAYOR VR RAMANATHAN RD CHETPUT 600031 INDIA TB RES CTR ICMR CHENNAI INDIA
Titolo Testata:
INDIAN JOURNAL OF MEDICAL RESEARCH
, volume: 108, anno: 1998,
pagine: 120 - 127
SICI:
0971-5916(1998)108:<120:EOTBRM>2.0.ZU;2-R
Fonte:
ISI
Lingua:
ENG
Soggetto:
MYCOBACTERIUM-TUBERCULOSIS; SPECIMENS; RECOVERY; MEDIA;
Keywords:
BACTEC RADIOMETRIC METHOD; DRUG SUSCEPTIBILITY TEST; MYCOBACTERIUM TUBERCULOSIS ISOLATION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
16
Recensione:
Indirizzi per estratti:
Citazione:
P. Venkataraman et al., "EVALUATION OF THE BACTEC RADIOMETRIC METHOD IN THE EARLY DIAGNOSIS OFTUBERCULOSIS", INDIAN JOURNAL OF MEDICAL RESEARCH, 108, 1998, pp. 120-127

Abstract

A comparison of the BACTEC radiometric method with the conventional culture and drug susceptibility testing methods on isolates from clinical specimens in pulmonary and extrapulmonary tuberculosis, childhood TB and TB in HIV-infected individuals was undertaken. In the case of pulmonary TB, the rate of isolation of positive cultures was significantly faster with the BACTEC method, with 87 per cent of the positives being obtained by 7 days, and 96 per cent by 14 days. However, while there was no difference in the total number of positive cultures by the two methods in smear positive pulmonary tuberculosis, in smear negativepulmonary TB, the BACTEC method yielded more number of positive cultures. In extrapulmonary TB, HIV-TB and childhood TB, although the BACTEC method did not yield additional positives, the detection of positives was considerably faster than by the conventional methods, in which the degree of growth was also scanty. The agreement in drug susceptibility tests was 94 per cent for streptomycin and isoniazid, 99 per cent for rifampicin and 91 per cent for ethambutol. Further, most of the drug susceptibility test results became available within 8 days by the BACTEC method. By facilitating early diagnosis, the BACTEC method may prove to be cost effective in a population with a high prevalence of tuberculosis, particularly in the extrapulmonary and paucibacillary forms of the disease.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/12/20 alle ore 10:40:49