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Titolo:
DOSE-DEPENDENT ACTION OF GLUCOSE ON MEMORY PROCESSES IN WOMEN - EFFECT ON SERIAL POSITION AND RECALL PRIORITY
Autore:
MESSIER C; PIERRE J; DESROCHERS A; GRAVEL M;
Indirizzi:
UNIV OTTAWA,SCH PSYCHOL,VANIER 215 OTTAWA ON K1N 6N5 CANADA UNIV QUEBEC,DEPT PSYCHOL MONTREAL PQ H3C 3P8 CANADA
Titolo Testata:
Cognitive brain research
fascicolo: 2, volume: 7, anno: 1998,
pagine: 221 - 233
SICI:
0926-6410(1998)7:2<221:DAOGOM>2.0.ZU;2-G
Fonte:
ISI
Lingua:
ENG
Soggetto:
COGNITIVE FUNCTIONS; GLYCEMIC CONTROL; ELDERLY HUMANS; YOUNG-ADULTS; ACETYLCHOLINE; ENHANCEMENT; TASKS; INJECTIONS; FRUCTOSE; RATS;
Keywords:
ACETYLCHOLINE; GLUCOSE; MEMORY; PRIMACY; PRIORITY INDEX; RECENCY; FREE RECALL;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
54
Recensione:
Indirizzi per estratti:
Citazione:
C. Messier et al., "DOSE-DEPENDENT ACTION OF GLUCOSE ON MEMORY PROCESSES IN WOMEN - EFFECT ON SERIAL POSITION AND RECALL PRIORITY", Cognitive brain research, 7(2), 1998, pp. 221-233

Abstract

Previous research has shown that glucose can enhance memory in animals and humans. In humans, the facilitative effect of glucose is best observed with declarative memory tasks in older subjects. While the memory-enhancing action of glucose is well established, the underlying physiological mechanisms and the specific aspects of memory that are modulated by glucose in humans are not well understood. The present study sought to examine the effects of glucose on memory in young women using a memory paradigm sensitive to specific encoding and retrieval strategies. The glucose dose was adjusted for the weight of each participant in order to generate a dose response curve covering most doses used in previous studies. The results showed that 300 mg/kg glucose enhanced the primacy effect as defined by the recall of the first five items of the lists. However, none of the doses of glucose produced changes in the recall priority given to primacy items. The effect of glucose appears to be localized on the recall primacy effect, suggesting that glucose acts on precise memory operations. This improvement, however, isindependent of the order in which subjects recalled the words. Cholinergic drugs have been shown to alter the recall of the primacy part ofword lists and this observation is consistent with the hypothesis that glucose acts on memory through an interaction with brain cholinergicsystems. (C) 1998 Elsevier Science B.V. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/01/20 alle ore 14:47:13