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Titolo:
LINEARITY AND ACCURACY ERRORS IN BONE DENSITOMETRY
Autore:
NIELSEN SP; BARENHOLDT O; DIESSEL E; ARMBRUST S; FELSENBERG D;
Indirizzi:
HILLEROD HOSP,DEPT CLIN PHYSIOL DK-3400 HILLEROD DENMARK UNIV HOSP BENJAMIN FRANKLIN,DEPT RADIOL,OSTEOPOROSIS RES GRP D-12200 BERLIN GERMANY
Titolo Testata:
British journal of radiology
fascicolo: 850, volume: 71, anno: 1998,
pagine: 1062 - 1068
Fonte:
ISI
Lingua:
ENG
Soggetto:
X-RAY ABSORPTIOMETRY; DXA PENCIL-BEAM; CROSS-CALIBRATION; FAN-BEAM; SPINE PHANTOM; IN-VITRO; PRECISION; STANDARDIZATION; OSTEOPOROSIS; DENSITY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
15
Recensione:
Indirizzi per estratti:
Citazione:
S.P. Nielsen et al., "LINEARITY AND ACCURACY ERRORS IN BONE DENSITOMETRY", British journal of radiology, 71(850), 1998, pp. 1062-1068

Abstract

This investigation was undertaken to quantify accuracy errors and identify possible linearity errors in dual energy X-ray absorptiometry (DXA) of bone, based on studies of commercially available bone densitometers for planar densitometry. The following was found in a combinationof in vitro phantom studies and in vivo investigations of human volunteers: (1) Pronounced differences between the instruments when measuring vertebral size and contours of the projected bone regions. (2) Falsely low bone mineral content (BMC in terms of g) in cases of low nominal bone mass, due to the fact that edge regions were omitted by the calculation software of some devices. (3) An increase in the projected bone area secondary to an increase in nominal bone mass with some instruments. (4) Clinically and statistically significant errors of accuracy of BMC and to a lesser extent bone mineral density (BMD). (5) Substantial linearity errors with some osteodensitometers for BMC, a phenomenon that reduces the usefulness of this parameter. It is concluded that DXA devices are affected by. a combination of accuracy errors and linearity errors, some more than others, and that linearity errors influence their ability to monitor change in BMC and to a lesser extent in BMD, making system intercomparison difficult.

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Documento generato il 04/12/20 alle ore 20:07:57