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Titolo:
TROPHOBLAST PSEUDO-VASCULOGENESIS - FAKING IT WITH ENDOTHELIAL ADHESION RECEPTORS
Autore:
DAMSKY CH; FISHER SJ;
Indirizzi:
UNIV CALIF SAN FRANCISCO,DEPT STOMATOL,HSW 604,513 PARNASSUS AVE SAN FRANCISCO CA 94143
Titolo Testata:
Current opinion in cell biology
fascicolo: 5, volume: 10, anno: 1998,
pagine: 660 - 666
SICI:
0955-0674(1998)10:5<660:TP-FIW>2.0.ZU;2-2
Fonte:
ISI
Lingua:
ENG
Soggetto:
PLACENTA GROWTH-FACTOR; INVASION IN-VITRO; HUMAN CYTOTROPHOBLASTS; ENDOVASCULAR INVASION; TARGETED DISRUPTION; SPIRAL ARTERIES; EARLY GESTATION; EARLY-PREGNANCY; DEFICIENT MICE; TIE2 RECEPTOR;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
72
Recensione:
Indirizzi per estratti:
Citazione:
C.H. Damsky e S.J. Fisher, "TROPHOBLAST PSEUDO-VASCULOGENESIS - FAKING IT WITH ENDOTHELIAL ADHESION RECEPTORS", Current opinion in cell biology, 10(5), 1998, pp. 660-666

Abstract

During early development, a subset of fetal (placental) cytotrophoblasts exhibits tumor-like behavior and invades the uterus. To access a supply of maternal blood, they invade arterioles and form heterotypic interactions with, and replace, resident maternal endothelium, creatinga hybrid uterine vasculature. Recently, it has become clear that invading cytotrophoblasts transform their adhesion receptor phenotype to resemble the endothelial cells they replace. Furthermore, they express vasculogenic factors and receptors. Is this a form of vasculogenesis?

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 22/09/20 alle ore 11:46:22