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Titolo:
VIRULENCE FACTORS OF STAPHYLOCOCCUS-AUREUS STRAINS CAUSING INFECTIVE ENDOCARDITIS - A COMPARISON WITH STRAINS FROM SKIN INFECTIONS
Autore:
HOGEVIK H; SODERQUIST B; TUNG HS; OLAISON L; WESTBERG A; RYDEN C; TARKOWSKI A; ANDERSSON R;
Indirizzi:
GOTHENBURG UNIV,DEPT INFECT DIS S-41685 GOTHENBURG SWEDEN OREBRO MED CTR HOSP,DEPT INFECT DIS S-70185 OREBRO SWEDEN UNIV UPPSALA,DEPT MED & PHYSIOL CHEM UPPSALA SWEDEN UNIV UPPSALA,DEPT INFECT DIS UPPSALA SWEDEN UNIV GOTHENBURG,DEPT CLIN IMMUNOL GOTHENBURG SWEDEN UNIV GOTHENBURG,DEPT RHEUMATOL GOTHENBURG SWEDEN
Titolo Testata:
APMIS. Acta pathologica, microbiologica et immunologica Scandinavica
fascicolo: 9, volume: 106, anno: 1998,
pagine: 901 - 908
SICI:
0903-4641(1998)106:9<901:VFOSSC>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Soggetto:
FIBRONECTIN; BINDING; OSTEOMYELITIS; EPIDEMIOLOGY; SIALOPROTEIN; ARTHRITIS; ADHERENCE; MATRIX;
Keywords:
INFECTIVE ENDOCARDITIS; STAPHYLOCOCCUS-AUREUS; ENTEROTOXIN; EXTRACELLULAR MATRIX PROTEINS; VIRULENCE FACTORS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
24
Recensione:
Indirizzi per estratti:
Citazione:
H. Hogevik et al., "VIRULENCE FACTORS OF STAPHYLOCOCCUS-AUREUS STRAINS CAUSING INFECTIVE ENDOCARDITIS - A COMPARISON WITH STRAINS FROM SKIN INFECTIONS", APMIS. Acta pathologica, microbiologica et immunologica Scandinavica, 106(9), 1998, pp. 901-908

Abstract

The objective was to study potential bacterial virulence factors in S. aureus endocarditis. S. aureus strains isolated from patients with well-classified episodes of infective endocarditis (IE) (n=26) were compared with control S. aureus strains from consecutive patients with skin infections (n=30). The potential virulence factors studied were Staphylococcal enterotoxin A-D (SEA, SEE, SEC, SED) and toxic shock syndrome toxin-1 (TSST-1) production and binding capacity to the extracellular matrix proteins: fibronectin, collagen type I, collagen type II and bone sialoprotein (BSP). None of the potential virulence factors studied was more prevalent among the IE strains. BSP binding was more often found in the control group with skin infections. Endocarditis patients with previous damage of the heart Valves were more often infected by strains not producing any enterotoxin. No correlation was found between the potential bacterial virulence factors studied and IE. Concerning the toxins known to act as superantigens (SEA-E and TSST-1), the tendencies in this and other studies indicate that a larger study groupmight identify them as pathogenic factors in a subgroup of staphylococcal endocarditis.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/05/20 alle ore 14:55:43