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Titolo:
GENERATION OF MYOCARDIAL FACTOR IMAGES DIRECTLY FROM THE DYNAMIC OXYGEN-15-WATER SCAN WITHOUT USE OF AN O-15 CARBON-MONOXIDE BLOOD-POOL SCAN
Autore:
HERMANSEN F; ASHBURNER J; SPINKS TJ; KOONER JS; CAMICI PG; LAMMERTSMA AA;
Indirizzi:
AARHUS GEN HOSP,PET CTR,44 NORREBROGADE DK-8000 AARHUS C DENMARK HAMMERSMITH HOSP,MRC,CTR CLIN SCI,CYCLOTRON UNIT,PET METHODOL GRP LONDON ENGLAND HAMMERSMITH HOSP,MRC,CTR CLIN SCI,CYCLOTRON UNIT,CARDIOL GRP LONDON ENGLAND HAMMERSMITH HOSP,ROYAL POSTGRAD MED SCH,DEPT CARDIOL LONDON ENGLAND
Titolo Testata:
The Journal of nuclear medicine
fascicolo: 10, volume: 39, anno: 1998,
pagine: 1696 - 1702
SICI:
0161-5505(1998)39:10<1696:GOMFID>2.0.ZU;2-P
Fonte:
ISI
Lingua:
ENG
Soggetto:
POSITRON EMISSION TOMOGRAPHY; LINEAR DIMENSION REDUCTION; TIME-ACTIVITY CURVES; MEDICAL IMAGES; TRANSMISSION TOMOGRAPHY; FLOW; PET; SEQUENCES; QUANTIFICATION; INPUT;
Keywords:
PET; MYOCARDIAL BLOOD FLOW; FACTOR ANALYSIS; MYOCARDIAL AND BLOOD-POOL IMAGES;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
20
Recensione:
Indirizzi per estratti:
Citazione:
F. Hermansen et al., "GENERATION OF MYOCARDIAL FACTOR IMAGES DIRECTLY FROM THE DYNAMIC OXYGEN-15-WATER SCAN WITHOUT USE OF AN O-15 CARBON-MONOXIDE BLOOD-POOL SCAN", The Journal of nuclear medicine, 39(10), 1998, pp. 1696-1702

Abstract

The measurement of regional myocardial blood flow (MBF) with (H2O)-O-15 and PET requires an additional (CO)-O-15 blood-pool scan for the purpose of region of interest (ROI) definition. This additional scan results in a substantially increased radiation dose, study duration and risk of movement artifacts. Therefore, a method was developed to generate myocardial factor images directly from the dynamic (H2O)-O-15 studywithout the need for a (CO)-O-15 scan. Methods: The factor sinograms were generated by means of linear dimension reduction of the dynamic sinograms, where the required variate and covariate factors (myocardialand blood time-activity curves) were modeled from the lung time-activity curve. The factor images were generated by iterative reconstruction. Results: No significant difference was found between MBF values from ROls drawn on the traditional images (using the (CO)-O-15 scan) and those drawn on the factor images. Conclusion: It is possible to generate myocardial images directly from the dynamic (H2O)-O-15 study, so that the (CO)-O-15 scan can be omitted from MBF studies. The proposed method is robust and results in nearly optimal signal-to-noise ratios inthe factor images.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/10/20 alle ore 01:22:15