Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
FIBRINOGEN AND FIBRINOLYSIS IN BLOOD AND IN THE ARTERIAL-WALL - ITS ROLE IN ADVANCED ATHEROSCLEROTIC DISEASE
Autore:
MARTINPAREDERO V; VADILLO J; DIAZ J; ESPINOSA A; BERGA C; SEGURA J; SANCHEZ J; BARBOD A; VILLAVERDE C; RICHARD CM;
Indirizzi:
UNIV HOSP JOAN XXIII,SERV VASC SURG,C DR MALLAFRE I GUASCH 4 TARRAGONA 43007 SPAIN
Titolo Testata:
Cardiovascular surgery
fascicolo: 5, volume: 6, anno: 1998,
pagine: 457 - 462
SICI:
0967-2109(1998)6:5<457:FAFIBA>2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Soggetto:
RISK FACTOR;
Keywords:
FIBRINOGEN; FIBRINOLYSIS; ATHEROSCLEROSIS; ARTERIAL WALL;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
18
Recensione:
Indirizzi per estratti:
Citazione:
V. Martinparedero et al., "FIBRINOGEN AND FIBRINOLYSIS IN BLOOD AND IN THE ARTERIAL-WALL - ITS ROLE IN ADVANCED ATHEROSCLEROTIC DISEASE", Cardiovascular surgery, 6(5), 1998, pp. 457-462

Abstract

High plasma fibrinogen appears to be an important risk factor for thedevelopment of atherosclerosis. The aim of our study was to measure fibrinogen and fibrin degradation products (D-dimer), interleukin-6 tissue plasminogen activator, plasminogen activator inhibitor-1 and urokinase-type plasminogen activator in the plasma and arterial walls of 45patients who had arterial surgery between April 1993 and November 1995. The arterial specimens were also examined by immunohistochemists for these same factors. The serum fibrinogen and fibrin degradation products were high in all patients. and fibrinolysis was depressed. Few leukocytes were seen in the arterial walls, which had poor fibrinolytic activity. Plasminogen-activator inhibitor activity in the wall was also reduced in the affected arterial walls. The abdominal aorta appearedto have the highest levels of fibrinogen and this may be related to its ability to form aneurysms. Fibrinogen may play an important role inthe progression of atherosclerotic disease. (C) 1998 The International Society for Cardiovascular Surgery. Published by Elsevier Science Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/03/20 alle ore 09:57:32