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Titolo:
Acetaminophen hepatotoxicity in a teenage, with excessive alcohol intake
Autore:
Fercovic, A; Serra, I; Serra, L;
Indirizzi:
Univ Chile, Escuela Salud Publ, Santiago, Chile Univ Chile Santiago Chile iv Chile, Escuela Salud Publ, Santiago, Chile Univ Chile, Hosp Quellon, Santiago, Chile Univ Chile Santiago ChileUniv Chile, Hosp Quellon, Santiago, Chile
Titolo Testata:
REVISTA MEDICA DE CHILE
fascicolo: 2, volume: 127, anno: 1999,
pagine: 202 - 205
SICI:
0034-9887(199902)127:2<202:AHIATW>2.0.ZU;2-L
Fonte:
ISI
Lingua:
SPA
Soggetto:
FULMINANT HEPATIC-FAILURE; THERAPEUTIC MISADVENTURE; TOXICITY; ETHANOL;
Keywords:
acetaminophen; drug hypersensitivity; hepatitis, toxic; liver failure, acute;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
21
Recensione:
Indirizzi per estratti:
Indirizzo: Serra, I UnivChilee, Escuela Salud Publ, Independencia 939,Casilla 70012, Santiago, Univ Chile Independencia 939,Casilla 70012 Santiago Chile iago,
Citazione:
A. Fercovic et al., "Acetaminophen hepatotoxicity in a teenage, with excessive alcohol intake", REV MED CHI, 127(2), 1999, pp. 202-205

Abstract

We report a 12 years old male with a history of excessive alcohol. intake,that developed a severe liver failure after the use of acetaminophen in therapeutic doses. He presented with encephalopathy, jaundice, fever and an upper gastrointestinal bleeding Serum aspartate aminotransferase values were5 250 IU/L. The patient received supportive care and oral corticosteroids,remained severely compromised for 72 hours and had a good evolution thereafter. The association of acetaminophen use and excessive alcohol intake in a patient who developed an acute hepatic failure and the absence of serological evidence of hepatitis A or B viral infection, support the diagnosis ofdrug induced liver failure.

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Documento generato il 29/02/20 alle ore 02:23:56