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Titolo:
Immunoblastic lymphadenopathy-like T-cell lymphoma complicated by multiplegastrointestinal involvement
Autore:
Kaneki, T; Kawashima, A; Akamatsu, T; Tanaka, N; Kubo, K; Koizumi, T; Sekiguchi, M; Hosaka, N; Honda, T; Koike, S; Adachi, W;
Indirizzi:
ShinshunUniv, Sch Med, Dept Internal Med 1, Matsumoto, Nagano 3908621, Japa Shinshu Univ Matsumoto Nagano Japan 3908621 tsumoto, Nagano 3908621, Japa
Titolo Testata:
JOURNAL OF GASTROENTEROLOGY
fascicolo: 2, volume: 34, anno: 1999,
pagine: 253 - 259
SICI:
0944-1174(199904)34:2<253:ILTLCB>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
ANGIOIMMUNOBLASTIC LYMPHADENOPATHY; HODGKINS-DISEASE; TRACT; DYSPROTEINEMIA; GRADE;
Keywords:
immunoblastic lymphadenopathy-like T-cell lymphoma; gastrointestinal involvement; peripheral T-cell lymphoma; gene rearrangement; perforative peritonitis;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
21
Recensione:
Indirizzi per estratti:
Indirizzo: Kaneki, T Shinshu3908621,ch Med, Dept Internal Med 1, 3-1-1 Asahi, Matsumoto, Nagano Shinshu Univ 3-1-1 Asahi Matsumoto Nagano Japan 3908621 , Nagano
Citazione:
T. Kaneki et al., "Immunoblastic lymphadenopathy-like T-cell lymphoma complicated by multiplegastrointestinal involvement", J GASTRO, 34(2), 1999, pp. 253-259

Abstract

We report a rare case of immunoblastic lymphadenopathy (IBL)-like T-cell lymphoma complicated by multiple gastrointestinal involvement, which appeared to be ameliorated by chemotherapy but resulted in perforative peritonitis. A 66-year-old Japanese woman who had generalized lymphadenopathy and eruptions was admitted to our hospital because of bloody stool. Colonoscopic examination revealed hemorrhagic ulcers in the terminal ileum and a saucer-like ulcer in the cecum. Gastrointestinal endoscopy revealed several ulcerative or elevated lesions in stomach and duodenum. Biopsy specimens of these lesions and of a lymph node showed characteristic histological features of IBL-like T-cell lymphoma. The initial treatment with prednisolone (PSL) and cyclophosphamide (CPA) was effective. Six months after the treatment, however, she developed bloody stool again caused by multiple ulcerative lesions in the large intestine. The recurrence of the disease was determined histologically, and four courses of CPA, PSL, vinblastine sulfate and doxorubicinhydrochloride (CHOP) therapy were administered. One month after completingthe CHOP therapy, she developed intestinal obstruction and then acute peritonitis resulting from perforation at an ulcer scar in the jejunum. Surgical treatment was successful, and histological examination demonstrated no lymphoma cells in the resected specimen, A gastrointestinal perforation should be recognized as a potential complication of IBL-like T-cell lymphoma, even during remission.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 12/07/20 alle ore 06:31:44