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Titolo:
Contribution of PET in the detection of liver metastases from pancreatic tumours
Autore:
Nakamoto, Y; Higashi, T; Sakahara, H; Tamaki, N; Kogire, M; Imamura, M; Konishi, J;
Indirizzi:
Kyoto Univ Hosp, Grad Sch Med, Dept Nucl Med, Kyoto 6068507, Japan Kyoto Univ Hosp Kyoto Japan 6068507 Dept Nucl Med, Kyoto 6068507, Japan Kyoto Univ Hosp, Grad Sch Med, Dept Diagnost Imaging, Kyoto 6068507, JapanKyoto Univ Hosp Kyoto Japan 6068507 agnost Imaging, Kyoto 6068507, Japan Kyoto Univ Hosp, Grad Sch Med, Dept Surg 1, Kyoto 6068507, Japan Kyoto Univ Hosp Kyoto Japan 6068507 d, Dept Surg 1, Kyoto 6068507, Japan Hokkaido Univ, Fac Med, Dept Nucl Med, Sapporo, Hokkaido 060, Japan Hokkaido Univ Sapporo Hokkaido Japan 060 ed, Sapporo, Hokkaido 060, Japan
Titolo Testata:
CLINICAL RADIOLOGY
fascicolo: 4, volume: 54, anno: 1999,
pagine: 248 - 252
SICI:
0009-9260(199904)54:4<248:COPITD>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Soggetto:
POSITRON EMISSION TOMOGRAPHY; CANCER; FLUORINE-18-FLUORODEOXYGLUCOSE; ADENOCARCINOMA; CARCINOMA; TUMORS; FDG; FLUORODEOXYGLUCOSE; ACCUMULATION; ARTERIAL;
Keywords:
liver metastases; FDG-PET; pancreatic cancer;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
24
Recensione:
Indirizzi per estratti:
Indirizzo: Nakamoto, Y KyotooUniv Hosp, Grad Sch Med, Dept Nucl Med, 54 Shogoin Kawahara Cho, Kyot Kyoto Univ Hosp 54 Shogoin Kawahara Cho Kyoto Japan 6068507 t
Citazione:
Y. Nakamoto et al., "Contribution of PET in the detection of liver metastases from pancreatic tumours", CLIN RADIOL, 54(4), 1999, pp. 248-252

Abstract

AIM: Although uptake of 2-deoxy-2-[fluorine-18]fluoro-D-glucose (FDG) in the liver is basically high, metastatic liver rumours are known to be positive on positron emission tomography (PET), The purpose of this study is to evaluate the diagnostic accuracy of FDG-PET in detecting hepatic metastases from pancreatic cancer. METHODS: Thirty-four patients with histologically proven malignant tumoursof the pancreas underwent FDG-PET,computed tomography (CT) and transabdominal ultrasound (US), The findings of PET, CT and US were compared with the histopathologic findings at surgery or with clinical follow-up and the diagnostic accuracy of PET was evaluated. RESULTS: PET showed 28 regions of high FDG uptake (SUV = 3.3-9.1) in 13 patients. Twenty-six foci were metastatic lesions confirmed by surgery (n = 11), clinical follow-up (n = 10) or autopsy (n = 5), FDG-PET accurately differentiated seven metastatic lesions from cysts when the diagnosis by US or CT was unreliable because of the small size of the lesion. In two patients who had areas of high uptake in the liver, no metastases were detected by surgery. FDG-PET showed no areas of increased uptake in 21 patients. Surgeryrevealed no metastatic lesions in the liver in 20 of 21 patients, but a liver metastasis was found at surgery in one patient. The diagnostic accuracyof FDG-PET was 90%, which was comparable with that of US or CT. CONCLUSION: Our data suggest that PET is reliable in detecting liver, metastases from pancreatic cancer.

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Documento generato il 01/12/20 alle ore 08:09:24