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Titolo:
NOTCH AND NEUROGENESIS
Autore:
BEATUS P; LENDAHL U;
Indirizzi:
KAROLINSKA INST,MED NOBEL INST,DEPT CELL & MOL BIOL S-17177 STOCKHOLMSWEDEN KAROLINSKA INST,MED NOBEL INST,DEPT CELL & MOL BIOL S-17177 STOCKHOLMSWEDEN
Titolo Testata:
Journal of neuroscience research
fascicolo: 2, volume: 54, anno: 1998,
pagine: 125 - 136
SICI:
0360-4012(1998)54:2<125:>2.0.ZU;2-D
Fonte:
ISI
Lingua:
ENG
Soggetto:
HELIX-LOOP-HELIX; EPITHELIAL-MESENCHYMAL INTERACTIONS; DOMINANT-NEGATIVE FORMS; CENTRAL-NERVOUS-SYSTEM; DOMAINS IN-VIVO; DROSOPHILA-NOTCH; CELL FATE; CAENORHABDITIS-ELEGANS; XENOPUS-EMBRYOS; DELTA-HOMOLOG;
Keywords:
NEUROGENESIS; RECEPTOR; INTRACELLULAR SIGNALING; RETINA; STROKE;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
85
Recensione:
Indirizzi per estratti:
Citazione:
P. Beatus e U. Lendahl, "NOTCH AND NEUROGENESIS", Journal of neuroscience research, 54(2), 1998, pp. 125-136

Abstract

The Notch signaling pathway has during the last few years emerged as an important signaling mechanism for communication between neighboringcells. Many of the components in the Notch signaling pathway have been identified and the pathway is important for cellular differentiationin various organs, including the nervous system. The Notch pathway ispivotal for a process called lateral inhibition, which ensures that cells differentiate to distinct fates from an initially homogenous cellpopulation. The aim of this review is to describe our current understanding of the molecular aspects of the Notch signaling pathway and to discuss its importance for nervous system development and disease. J. Neurosci. Res. 54:125-136, 1998. (C) 1998 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 09/07/20 alle ore 13:51:12