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Titolo:
LEG MASS AND LOWER-BODY NEGATIVE-PRESSURE TOLERANCE IN MEN AND WOMEN
Autore:
LAWLER LA; HALLIWILL JR; SUMMER JN; JOYNER MJ; MULVAGH SL;
Indirizzi:
MAYO CLIN & MAYO FDN,DEPT ANESTHESIOL,200 1ST ST SW ROCHESTER MN 55905 MAYO CLIN & MAYO FDN,DEPT ANESTHESIOL ROCHESTER MN 55905 MAYO CLIN & MAYO FDN,DEPT PHYSIOL & BIOPHYS ROCHESTER MN 55905 MAYO CLIN & MAYO FDN,DIV CARDIOVASC DIS & INTERNAL MED ROCHESTER MN 55905
Titolo Testata:
Journal of applied physiology (1985)
fascicolo: 4, volume: 85, anno: 1998,
pagine: 1471 - 1475
SICI:
8750-7587(1998)85:4<1471:LMALNT>2.0.ZU;2-T
Fonte:
ISI
Lingua:
ENG
Soggetto:
VASOCONSTRICTOR RESPONSES; ORTHOSTATIC INTOLERANCE; SIZE;
Keywords:
ORTHOSTATIC TOLERANCE; BODY COMPOSITION; VASOCONSTRICTION; VASCULAR COMPLIANCE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
14
Recensione:
Indirizzi per estratti:
Citazione:
L.A. Lawler et al., "LEG MASS AND LOWER-BODY NEGATIVE-PRESSURE TOLERANCE IN MEN AND WOMEN", Journal of applied physiology (1985), 85(4), 1998, pp. 1471-1475

Abstract

To explore the hypothesis that lower body muscle mass correlates withorthostatic tolerance, 18 healthy volunteers (age 18-48 yr; 10 men, 8women) underwent a graded lower body negative pressure (LBNP) protocol consisting of six, 5-min stages of suction up to 60 mmHg in 10-mmHg increments. Forearm blood flow, heart rate, and blood pressure were measured, and forearm vascular resistance was calculated. Leg muscle mass was assessed by dual-energy X-ray absorptiometry. All subjects received standard intravenous hydration for at least 8 h before the study. Six men and four women completed all stages of LBNP. Four men and fourwomen developed presyncopal symptoms, including marked bradycardia and/or hypotension, at LBNP levels of 30 mmHg (n = 2; 1 man, 1 woman), 40 mmHg (n = 2; 1 man, 1 woman), and 50 mmHg (n = 4; 2 men, 2 women). The presyncopal subjects had leg muscle masses ranging from 19.5 to 25.2 kg in men and from 11.7 to 16.6 kg in women. In subjects who completed all stages of LBNP, leg muscle mass ranged from 17.5 to 24.1 kg in men and from 10.4 to 18.0 kg in women. Leg muscle mass did not differ between presyncopal subjects and those who completed the protocol. Furthermore, there were no differences in the hemodynamic responses to LBNP between subjects with low vs, high leg mass. These data suggest that leg muscle mass is not a critical determinant of LBNP tolerance in otherwise healthy men and women.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/09/20 alle ore 09:26:38