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Titolo:
FIBER-TYPE AND CITRATE SYNTHASE ACTIVITY IN THE HUMAN GASTROCNEMIUS AND VASTUS LATERALIS WITH AGING
Autore:
HOUMARD JA; WEIDNER ML; GAVIGAN KE; TYNDALL GL; HICKEY MS; ALSHAMI A;
Indirizzi:
E CAROLINA UNIV,HUMAN PERFORMANCE LAB,DEPT EXERCISE & SPORT SCI,WARD SPORTS MED BLDG GREENVILLE NC 27858
Titolo Testata:
Journal of applied physiology (1985)
fascicolo: 4, volume: 85, anno: 1998,
pagine: 1337 - 1341
SICI:
8750-7587(1998)85:4<1337:FACSAI>2.0.ZU;2-R
Fonte:
ISI
Lingua:
ENG
Soggetto:
HUMAN SKELETAL-MUSCLE; ELDERLY MEN; AEROBIC POWER; IN-VIVO; AGE; WOMEN; MORPHOLOGY; YOUNG; METABOLISM; STRENGTH;
Keywords:
EXERCISE; BODY COMPOSITION; MAXIMAL OXYGEN CONSUMPTION; RESPIRATORY CAPACITY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
31
Recensione:
Indirizzi per estratti:
Citazione:
J.A. Houmard et al., "FIBER-TYPE AND CITRATE SYNTHASE ACTIVITY IN THE HUMAN GASTROCNEMIUS AND VASTUS LATERALIS WITH AGING", Journal of applied physiology (1985), 85(4), 1998, pp. 1337-1341

Abstract

The purpose of this study was to determine whether enzymatic and histochemical characteristics of human skeletal muscle are altered with aging. Tissues from the vastus lateralis (VL) and gastrocnemius were analyzed for citrate synthase (CS) activity and fiber type in 55 sedentary men (age range 18-80 yr). In this population, CS activity in the gastrocnemius was negatively related to age (r = -0.32, P < 0.05); there was no relationship in the VL. Treadmill-determined maximal oxygen consumption was positively related (r = 0.40, P < 0.05) to CS in the gastrocnemius but not in the VL. CS activity in the gastrocnemius was 24% lower in the oldest (greater than or equal to 60 yr, n = 10) vs. the youngest (less than or equal to 30 yr; n = 12) men; there was no changein CS activity in the VL with aging. No changes in fiber type were evident with age in either muscle. These data suggest a reduction in oxidative enzyme activity in human skeletal muscle with the aging process; this relationship may be muscle-group specific.

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Documento generato il 03/12/20 alle ore 05:12:40