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Titolo:
DOPAMINE D-2 RECEPTOR DENSITY AND PERSONAL DETACHMENT IN HEALTHY-SUBJECTS
Autore:
BREIER A; KESTLER L; ADLER C; ELMAN I; WIESENFELD N; MALHOTRA A; PICKAR D;
Indirizzi:
ELI LILLY & CO,LILLY CORP CTR,DROP CODE 0538 INDIANAPOLIS IN 46285 NIMH,EXPT THERAPEUT BRANCH BETHESDA MD 20892
Titolo Testata:
The American journal of psychiatry
fascicolo: 10, volume: 155, anno: 1998,
pagine: 1440 - 1442
SICI:
0002-953X(1998)155:10<1440:DDRDAP>2.0.ZU;2-G
Fonte:
ISI
Lingua:
ENG
Soggetto:
SCHIZOPHRENIA; TRAITS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Physical, Chemical & Earth Sciences
Science Citation Index Expanded
Citazioni:
8
Recensione:
Indirizzi per estratti:
Citazione:
A. Breier et al., "DOPAMINE D-2 RECEPTOR DENSITY AND PERSONAL DETACHMENT IN HEALTHY-SUBJECTS", The American journal of psychiatry, 155(10), 1998, pp. 1440-1442

Abstract

Objective: The purpose of this study was to examine the relationship between the personality trait involving personal detachment and dopamine D-2 receptor specific binding in healthy subjects. Method: Eighteenadult subjects completed the Karolinska Scales of Personality and theTridimensional Personality Questionnaire and participated in a study that used [C-11]raclopride positron emission tomography (PET) to quantify striatal D-2 receptor binding. Results: A significant relationshipwas found between D-2 receptor specific binding and detachment scoreson the Karolinska Scales of Personality but not between D-2 receptor specific binding and attachment scores on the Tridimensional Personality Questionnaire. in an exploratory analysis, the authors found a significant relationship between binding and the sentimentality cluster onthe Tridimensional Personality Questionnaire but on no other personality clusters scores on the Tridimensional Personality Questionnaire orKarolinska Scales of Personality. Conclusions: These findings replicate those of a recent report that personal detachment scores on the Karolinska Scales of Personality are related to dopamine D-2 receptor density and extends this finding by suggesting that the relationship is relatively specific to the trait defined by the Karolinska Scales of Personality and does not generalize to other forms of detachment.

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Documento generato il 22/09/20 alle ore 17:20:26