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Titolo:
FACILE ACCESS TO 4-ARYL-2(5H)-FURANONES BY SUZUKI CROSS-COUPLING - EFFICIENT SYNTHESIS OF RUBROLIDE-C AND RUBROLIDE-E
Autore:
BOUKOUVALAS J; LACHANCE N; OUELLET M; TRUDEAU M;
Indirizzi:
UNIV LAVAL,DEPT CHIM ST FOY PQ G1K 7P4 CANADA
Titolo Testata:
Tetrahedron letters
fascicolo: 42, volume: 39, anno: 1998,
pagine: 7665 - 7668
SICI:
0040-4039(1998)39:42<7665:FAT4BS>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Soggetto:
GAMMA-ALKYLIDENEBUTENOLIDES; BUT-2-ENOLIDES; HETEROCYCLES; LACTONES; ESTERS; ACID;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
30
Recensione:
Indirizzi per estratti:
Citazione:
J. Boukouvalas et al., "FACILE ACCESS TO 4-ARYL-2(5H)-FURANONES BY SUZUKI CROSS-COUPLING - EFFICIENT SYNTHESIS OF RUBROLIDE-C AND RUBROLIDE-E", Tetrahedron letters, 39(42), 1998, pp. 7665-7668

Abstract

The Pd(0)-catalyzed cross coupling between 4-bromo-2(5H)-furanones and arylboronic acids provides the corresponding 4-aryl-2(5H)-furanones in yields of 61-85%. By using this method in conjunction with furanolate chemistry, the marine antibiotics rubrolide C and E have been synthesized in highly efficient fashion (4 steps, overall yield = 61 and 56% respectively) from beta-tetronic acid. (C) 1998 Elsevier Science Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 24/09/20 alle ore 07:08:14