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Titolo:
DELAYED RECOVERY OF AUDITORY CORTICAL EVOKED-POTENTIALS IS CORRELATEDWITH CORTICAL NEURONAL DEATH AFTER TRANSIENT CEREBRAL-ISCHEMIA IN AWAKE GERBILS
Autore:
ICHIKI H; KUROIWA T; TANIGUCHI I; OKEDA R;
Indirizzi:
TOKYO MED & DENT UNIV,MED RES INST,DEPT NEUROPATHOL,BUNKYO KU,YUSHIMA1-5-45 TOKYO 113 JAPAN TOKYO MED & DENT UNIV,MED RES INST,DEPT NEUROPATHOL,BUNKYO KU TOKYO 113 JAPAN TOKYO MED & DENT UNIV,MED RES INST,DEPT NEUROPHYSIOL TOKYO JAPAN JAPAN SELF DEF FORCES CENT HOSP,DEPT OTOLARYNGOL TOKYO JAPAN
Titolo Testata:
Brain research
fascicolo: 2, volume: 806, anno: 1998,
pagine: 278 - 281
SICI:
0006-8993(1998)806:2<278:DROACE>2.0.ZU;2-8
Fonte:
ISI
Lingua:
ENG
Soggetto:
BLOOD-FLOW; BRAIN; SYSTEMS; CORTEX; DAMAGE;
Keywords:
MIDDLE-LATENCY AUDITORY EVOKED POTENTIAL; GERBIL; AUDITORY CORTEX; TRANSIENT CEREBRAL ISCHEMIA; NEURONAL DEATH;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
20
Recensione:
Indirizzi per estratti:
Citazione:
H. Ichiki et al., "DELAYED RECOVERY OF AUDITORY CORTICAL EVOKED-POTENTIALS IS CORRELATEDWITH CORTICAL NEURONAL DEATH AFTER TRANSIENT CEREBRAL-ISCHEMIA IN AWAKE GERBILS", Brain research, 806(2), 1998, pp. 278-281

Abstract

Early detection of irreversible neuronal change after transient cerebral ischemia is important so that adequate treatment can be initiated within the therapeutic window. We have examined the correlation between changes in middle-latency auditory evoked potentials (MAEPs) and histological changes in the auditory cortex of awake Mongolian gerbils subjected to 4 min or 12 min of transient cerebral ischemia. Post-ischemic MAEPs were characterized by the appearance of a markedly large negative and positive component at approximately 17-22 ms latency in both groups. Delay in the appearance of the high amplitude (maximal amplitude at 45 min after recirculation in the 12-min ischemia group) precedes the slowly developing death of neurons in the auditory cortex that results from transient cerebral ischemia. (C) 1998 Elsevier Science B.V. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/01/20 alle ore 07:23:43