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Titolo:
SEQUENCING AND FUNCTIONAL-ANALYSIS OF THE YEAST GENOME
Autore:
ZAGULSKI M; HERBERT CJ; RYTKA J;
Indirizzi:
POLISH ACAD SCI,INST BIOCHEM & BIOPHYS,A PAWINSKIEGO 5A PL-02106 WARSAW POLAND POLISH ACAD SCI,INST BIOCHEM & BIOPHYS PL-02106 WARSAW POLAND UNIV PARIS 06,CTR GENET MOL,LAB PROPRE,CNRS F-91198 GIF SUR YVETTE FRANCE
Titolo Testata:
Acta Biochimica Polonica
fascicolo: 3, volume: 45, anno: 1998,
pagine: 627 - 643
SICI:
0001-527X(1998)45:3<627:SAFOTY>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
PROTEIN-PROTEIN INTERACTIONS; OPEN READING FRAMES; ORDERED CLONE BANK; SACCHAROMYCES-CEREVISIAE; GENE-EXPRESSION; ESCHERICHIA-COLI; CHROMOSOME-III; PCR; RESISTANCE; SCALE;
Keywords:
YEAST; SACCHAROMYCES CEREVISIAE; GENOMICS; GENOME SEQUENCE; GENE FUNCTION;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
52
Recensione:
Indirizzi per estratti:
Citazione:
M. Zagulski et al., "SEQUENCING AND FUNCTIONAL-ANALYSIS OF THE YEAST GENOME", Acta Biochimica Polonica, 45(3), 1998, pp. 627-643

Abstract

The genome of the yeast Saccharomyces cerevisiae was sequenced by an international consortium of laboratories from Europe, Canada, the U.S.A. and Japan. This project is now finished and the complete sequence of the first eukaryotic genome was released to the public data bases inApril 1996. An overview and preliminary analysis of the entire genomesequence was presented in a special issue of Nature in May 1997, entitled ''The yeast genome directory''. At its origin the Yeast Genome Sequencing Project provoked much debate and controversy; however, the final results obtained and the insights this has given us into the organisation and content of a eukaryotic genome have more than justified the expectations of the supporters of the project. The importance of genomic sequencing and analysis, especially of model organisms, is now widely accepted and this has resulted in the birth of the new science ofgenomics (Botstein & Cherry, 1997, Proc. Natl. Acad, Sci. U.S.A. 94, 5506). The information from gene and protein sequences ultimately leadto functional description of all genes. The main strategies describing possible ways to analyse the function of new genes that have been identified by systematic sequencing of Saccharomyces cerevisiae genome are described.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/11/20 alle ore 17:03:11