Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
DISTRIBUTION PATTERN AND RISK-FACTORS OF PELVIC AND PARAAORTIC LYMPH-NODE METASTASIS IN EPITHELIAL OVARIAN-CARCINOMA
Autore:
TSUMURA N; SAKURAGI N; HAREYAMA H; SATOH C; OIKAWA M; YAMADA H; YAMAMOTO R; OKUYAMA K; FUJINO T; SAGAWA T; FUJIMOTO S;
Indirizzi:
HOKKAIDO UNIV,SCH MED,DEPT OBSTET & GYNECOL,NORTH 15,WEST 7 SAPPORO HOKKAIDO 060 JAPAN HOKKAIDO UNIV,SCH MED,DEPT OBSTET & GYNECOL SAPPORO HOKKAIDO 060 JAPAN
Titolo Testata:
International journal of cancer
fascicolo: 5, volume: 79, anno: 1998,
pagine: 526 - 530
SICI:
0020-7136(1998)79:5<526:DPAROP>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Soggetto:
PARAAORTIC LYMPHADENECTOMY; STAGE-I; CANCER; SITES;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
18
Recensione:
Indirizzi per estratti:
Citazione:
N. Tsumura et al., "DISTRIBUTION PATTERN AND RISK-FACTORS OF PELVIC AND PARAAORTIC LYMPH-NODE METASTASIS IN EPITHELIAL OVARIAN-CARCINOMA", International journal of cancer, 79(5), 1998, pp. 526-530

Abstract

The distribution of lymph node metastasis and the clinicopathologic risk factors for nodal involvement in ovarian carcinoma need to be clarified based on systematic lymph node dissection. We studied 115 patients with ovarian carcinoma who underwent systematic pelvic and para-aortic lymph node dissection between 1987 and 1997, The incidence and distribution of lymph node metastasis are described and the clinico-pathologic risk factors for nodal involvement are investigated, Based on the occurrence of lymph node metastasis in the early stages, the incidence of solitary node involvement and the distribution of lymph node metastasis, we conclude that the primary site of nodal involvement in ovarian carcinoma is the para-aortic node (PAN), especially PAN superior to the inferior mesenteric artery (IMA). By univariate analysis, clinical stage, histologic type (mucinous vs. others), grade, multiple peritoneal metastases, peritoneal cytology, volume of ascites and serum CA125 level were correlated with overall incidence of lymph node metastasis. By performing a multivariate analysis with the clinical stage excluded, it was revealed that grade and peritoneal cytology were independent factors for PAN metastasis (p < 0.0025 and < 0.001, respectively)and that multiple peritoneal metastases and PAN metastasis were significant predictors of pelvic node metastasis (p < 0.01 and < 0.005, respectively). In conclusion, the PANs superior and inferior to IMA should be explored in staging of ovarian carcinoma thar appears to be confined to the ovaries. To determine accurately the extent of disease, both the para-aortic and pelvic areas may need to be sampled or dissectedin the case of ovarian carcinoma involving the peritoneal surfaces. Int. J. Cancer (Pred. Oncol.) 79:526-530, 1998. (C) 1998 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/11/20 alle ore 16:49:28