Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
COX MULTIVARIATE REGRESSION-MODELS FOR ESTIMATING PROGNOSIS OF PATIENTS WITH ENDOMETRIOID ADENOCARCINOMA OF THE UTERINE CORPUS WHO UNDERWENT THOROUGH SURGICAL STAGING
Autore:
NISHIYA M; SAKURAGI N; HAREYAMA H; EBINA Y; FURUYA M; OIKAWA M; YAMAMOTO R; FUJINO T; FUJIMOTO S;
Indirizzi:
HOKKAIDO UNIV,SCH MED,DEPT OBSTET & GYNECOL SAPPORO HOKKAIDO 060863 JAPAN HOKKAIDO UNIV,SCH MED,DEPT OBSTET & GYNECOL SAPPORO HOKKAIDO 060863 JAPAN
Titolo Testata:
International journal of cancer
fascicolo: 5, volume: 79, anno: 1998,
pagine: 521 - 525
SICI:
0020-7136(1998)79:5<521:CMRFEP>2.0.ZU;2-C
Fonte:
ISI
Lingua:
ENG
Soggetto:
PERITONEAL CYTOLOGY; CARCINOMA; INVASION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
18
Recensione:
Indirizzi per estratti:
Citazione:
M. Nishiya et al., "COX MULTIVARIATE REGRESSION-MODELS FOR ESTIMATING PROGNOSIS OF PATIENTS WITH ENDOMETRIOID ADENOCARCINOMA OF THE UTERINE CORPUS WHO UNDERWENT THOROUGH SURGICAL STAGING", International journal of cancer, 79(5), 1998, pp. 521-525

Abstract

The International Federation of Gynecology and Obstetrics (FIGO) adopted surgical staging criteria in 1988. Many studies have shown that histologic grade, nuclear grade, lymphvascular space invasion and cell type are also important predictors of survival. It has not been clarified, however, how to integrate these histopathologic variables into theprocess of estimating individual prognosis. We performed Cox multivariate regression analysis to create models that incorporate various histopathologic factors for estimating the prognoses of patients with endometrioid adenocarcinoma of the uterine corpus. Our study was based ondata from 206 patients who underwent complete surgical staging, including systematic pelvic and para-aortic lymph node dissection. Two models resulted: one included depth of myometrial invasion, paraaortic node metastasis and the number of sites involved by the tumor among the cervix, ovary and pelvic lymph nodes (which we designated as extracorporeal spread score, ECS) and the other incorporated nuclear grade and lymph-vascular space invasion as variables. These 2 models enabled the prognosis for patients with endometrioid adenocarcinoma to be stratified into several levels according to hazard ratio. Comprehensive integration of the histopathologic prognostic factors, categorized into those relating to tumor extent and those relating to tumor virulence, should facilitate the estimation of individual prognosis more accurately than FIGO staging alone. Int. J. Cancer (Pred. Oncol.) 79:521-525, 1998. (C) 1998 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/11/20 alle ore 00:44:09