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Titolo:
AMERICAN-INDIAN HERITAGE AND RISK-FACTORS FOR RENAL INJURY
Autore:
KASISKE BL; RITHNAJARIAN S; CASPER ML; CROFT JB;
Indirizzi:
HENNEPIN CTY MED CTR,DEPT MED,DIV NEPHROL,701 PK AVE MINNEAPOLIS MN 55404 INDIAN HLTH SERV,BEMIDJI AREA OFF,DIABET PROGRAM BEMIDJI MN 00000 CTR DIS CONTROL & PREVENT,NATL CTR CHRON DIS PREVENT & HLTH PROMOT,CARDIOVASC HLTH BRANCH ATLANTA GA 00000
Titolo Testata:
Kidney international
fascicolo: 4, volume: 54, anno: 1998,
pagine: 1305 - 1310
SICI:
0085-2538(1998)54:4<1305:AHARFR>2.0.ZU;2-P
Fonte:
ISI
Lingua:
ENG
Soggetto:
PIMA-INDIANS; DIABETES-MELLITUS; BLOOD-PRESSURE; DISEASE; HEALTH; KIDNEY; MICROALBUMINURIA; HYPERTENSION; PROTEINURIA; ALBUMINURIA;
Keywords:
GREAT LAKES POPULATION; ALBUMINURIA; DIABETES; HYPERTENSION; MYOCARDIAL INFARCTION; AMERICAN INDIAN HERITAGE; SOCIOECONOMIC STATUS AND HEALTH; CARDIOVASCULAR DISEASE; INTERTRIBAL HEART PROJECT;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
26
Recensione:
Indirizzi per estratti:
Citazione:
B.L. Kasiske et al., "AMERICAN-INDIAN HERITAGE AND RISK-FACTORS FOR RENAL INJURY", Kidney international, 54(4), 1998, pp. 1305-1310

Abstract

Background. Little is known about the causes and consequences of renal disease among American Indians in the Great Lakes region of the United States. Methods. We examined clinical correlates of albumin/creatinine ratios among 1368 participants in the three tribal communities of the Inter-Tribal Heart Project using univariate and multivariate analysis. Results. Compared to 1086 participants without albuminuria, the 240 with microalbuminuria (30 to 299 mg/g) and the 42- with macroalbuminuria (>300 mg/g) were more likely to report a history of a myocardialinfarction (6.4%, 16.0%, and 23.8%, respectively, P < 0.001). Similarly, compared to patients without albuminuria, those with microalbuminuria and macroalbuminuria were more likely to report a history of stroke (2.3%, 8.4% and 26.2%, respectively, P < 0.001). In a multiple linear regression model, independent correlates of albumin excretion (P < 0.05) included: fasting blood sugar, treated diabetes, treated hypertension, higher systolic blood pressure, lower diastolic blood pressure, abnormal electrocardiogram, a history of stroke, the degree of American Indian heritage, and lower household income. Conclusions. Urinary albumin excretion is associated with cardiovascular disease outcomes andrisk factors among American Indians of the Great Lakes region. Both heredity and socioeconomic status appear to play a role in the pathogenesis of renal injury in this population.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 09/07/20 alle ore 16:58:28