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Titolo:
CHANGES IN SERUM LEVELS OF SIALOGLYCOPROTEINS IN MICE EXPOSED TO UV-BRADIATION
Autore:
YAMAMOTO K; FURUYA T; KAMEOKA Y; KAWANAKA M;
Indirizzi:
NATL INST INFECT DIS,DEPT VIROL 1,SHINJUKU KU,1-23-1 TOYAMA TOKYO 1628640 JAPAN NATL INST INFECT DIS,DIV GENET RESOURCES,SHINJUKU KU TOKYO 1628640 JAPAN NATL INST INFECT DIS,DEPT PARASITOL,SHINJUKU KU TOKYO 1628640 JAPAN
Titolo Testata:
Biological & pharmaceutical bulletin
fascicolo: 9, volume: 21, anno: 1998,
pagine: 1000 - 1002
SICI:
0918-6158(1998)21:9<1000:CISLOS>2.0.ZU;2-S
Fonte:
ISI
Lingua:
ENG
Soggetto:
PLASMA-PROTEIN BINDING; ACUTE PHASE PROTEINS; ALPHA-1-ACID GLYCOPROTEIN; INTERLEUKIN-6; MICROHETEROGENEITY; IRRADIATION; DISEASE; MOUSE; LIGHT; LUPUS;
Keywords:
UV-B; ACUTE PHASE REACTANT; SIALOGLYCOPROTEIN; HAPTOGLOBIN; HEMOPEXIN; SIALIC ACID STAINING;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
32
Recensione:
Indirizzi per estratti:
Citazione:
K. Yamamoto et al., "CHANGES IN SERUM LEVELS OF SIALOGLYCOPROTEINS IN MICE EXPOSED TO UV-BRADIATION", Biological & pharmaceutical bulletin, 21(9), 1998, pp. 1000-1002

Abstract

In the acute phase reaction, hepatocytes in the liver are activated and increase the plasma levels of acute phase reactants. Our previous study has shown that plasma sialic acid, an acute phase reactant, was increased following exposure of mice to UV-B radiation. Plasma sialic acid is derived from many plasma components. To clarify the type of plasma sialic acid that is increased by exposure to UV-B radiation, we performed two-dimensional electrophoresis and staining for sialic acid. Consequently, the increases in haptoglobin and hemopexin were marked and 90% or more of the increased sialic acid was derived from these twoglycoproteins after exposure to UV radiation. The increase in alpha(1)-acid glycoprotein levels was slight and did not contribute to the total increase in plasma sialic acid after exposure to UV radiation, Plasma levels of several proteins including antichymotrypsin (ACT), were reduced following exposure to UV radiation. The discrepancy between our results and published ones regarding ACT levels are discussed in terms of the type of cytokine.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/04/20 alle ore 09:30:12