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Titolo:
FERULIC ACID DEHYDRODIMERS FROM WHEAT BRAN - ISOLATION, PURIFICATION AND ANTIOXIDANT PROPERTIES OF 8-O-4-DIFERULIC ACID
Autore:
GARCIACONESA MT; PLUMB GW; WALDRON KW; RALPH J; WILLIAMSON G;
Indirizzi:
AFRC,INST FOOD RES,DEPT BIOCHEM,NORWICH RES PK NORWICH NR4 7UA NORFOLK ENGLAND AFRC,INST FOOD RES,DEPT BIOCHEM NORWICH NR4 7UA NORFOLK ENGLAND AGR RES SERV,US DAIRY FORAGE RES CTR,USDA MADISON WI 00000
Titolo Testata:
Redox report
fascicolo: 5-6, volume: 3, anno: 1997,
pagine: 319 - 323
SICI:
1351-0002(1997)3:5-6<319:FADFWB>2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Soggetto:
OXIDATIVE CROSS-LINKING; CELL-WALLS; DIFERULIC ACID; IDENTIFICATION; RADICALS; DIMERS;
Tipo documento:
Article
Natura:
Periodico
Citazioni:
20
Recensione:
Indirizzi per estratti:
Citazione:
M.T. Garciaconesa et al., "FERULIC ACID DEHYDRODIMERS FROM WHEAT BRAN - ISOLATION, PURIFICATION AND ANTIOXIDANT PROPERTIES OF 8-O-4-DIFERULIC ACID", Redox report, 3(5-6), 1997, pp. 319-323

Abstract

Wheat bran contains several ester-linked dehydrodimers of ferulic acid, which were detected and quantified after sequential alkaline hydrolysis. The major dime rs released were: enyl)-7-methoxy-2,3-dihydrobenzofuran-3-carboxylic acid (5-8-BendiFA), yl]-2-methoxy-phenoxy}-4-hydroxy-3-methoxycinnamic acid (8-O-4-diFA) and E,E)-4,4'-dihydroxy-5,5'-dimethoxy-3,3'-bicinnamic acid (5-5-diFA). 6-melhoxy-1,2-dihydro-naphthalene-2,3-dicarboxylic acid (8-8-diFA cyclic form) and ,4'-dihydroxy-3,3'-dimethoxy-beta,beta'-bicinnamic acid (8-8-diFA non cyclic form) were not detected. One of the most abundant dimers, 8-O-4-diFA, was purified from de-starched wheat bran after alkaline hydrolysis and preparative HPLC. The resultant product was identical to the chemically synthesised 8-O-4-dimer by TLC and HPLC as confirmed by H-1-NMR and mass spectrometry. The absorption maxima and absorption coefficients for the synthetic compound in ethanol were: lambda(max): 323 nm, lambda(min): 258 nm, epsilon(lambda min) (M(-1)cm(-1)): 24800 +/- 2100 and epsilon(280) (M(-1)cm(-1)): 19700 +/- 1100. The antioxidant properties of 8-O-4-diFA were assessed using: (a) inhibition of ascorbate/iron-induced peroxidation of phosphatidylcholine liposomes and; (b) scavenging of theradical cation of 2,2'-azinobis (3-ethyl-benzothiazoline-6-sulphonate) (ABTS) relative to the water-soluble vitamin E analogue, Trolox C. The 8-O-4-diFA was a better antioxidant than ferulic acid in both lipidand aqueous phases. This is the first report of the antioxidant activity of a natural diferulate obtained from a plant.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/09/20 alle ore 19:47:36