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Titolo:
CRYOFIBRINOGENEMIA - AN ADDITION TO THE DIFFERENTIAL-DIAGNOSIS OF CALCIPHYLAXIS IN END-STAGE RENAL-DISEASE
Autore:
SANKARASUBBAIYAN S; SCOTT G; HOLLEY JL;
Indirizzi:
UNIV ROCHESTER,MED CTR,NEPHROL UNIT,BOX 675,601 ELMWOOD AVE ROCHESTERNY 14642 UNIV ROCHESTER,MED CTR,DERMATOL UNIT ROCHESTER NY 14642 UNIV ROCHESTER,MED CTR,PATHOL UNIT ROCHESTER NY 14642
Titolo Testata:
American journal of kidney diseases
fascicolo: 3, volume: 32, anno: 1998,
pagine: 494 - 498
SICI:
0272-6386(1998)32:3<494:C-AATT>2.0.ZU;2-G
Fonte:
ISI
Lingua:
ENG
Soggetto:
SKIN NECROSIS; STANOZOLOL; FAILURE;
Keywords:
CRYOFIBRINOGENEMIA; CALCIPHYLAXIS; THROMBOEMBOLIC DISORDERS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
18
Recensione:
Indirizzi per estratti:
Citazione:
S. Sankarasubbaiyan et al., "CRYOFIBRINOGENEMIA - AN ADDITION TO THE DIFFERENTIAL-DIAGNOSIS OF CALCIPHYLAXIS IN END-STAGE RENAL-DISEASE", American journal of kidney diseases, 32(3), 1998, pp. 494-498

Abstract

Cryofibrinogenemia is a disorder characterized by cryoprecipitation with variable clinical presentation that was first described by Korst and Kratochvil in 1955, Cryofibrinogen is a cold insoluble complex of fibrin, fibrinogen, and fibrin split products with albumin, cold insoluble globulin, factor VIII, and plasma proteins. Cryofibrinogenemia is associated with metastatic malignancies, collagen vascular diseases, and thromboembolic disorders and may be clinically asymptomatic or present with thromboembolic phenomena of skin and viscera. The pathogenesis of cryofibrinogenemia is unknown. It may be caused by the inhibitionof fibrinolysis, leading to an accumulation of cryofibrinogen, Treatment of cryofibrinogenemia may include Stanozolol, plasmapheresis, and fibrinolytics. Cryofibrinogenemia simulates calciphylaxis clinicopathologically, because both may present with skin necrosis. Calciphylaxis has been reported in end-stage renal disease, but we report the first case of cryofibrinogen in a chronic dialysis patient. We suggest that in the appropriate clinical setting, cryofibrinogenemia should be considered in the differential diagnosis of calciphylaxis, and serum cryofibrinogen levels should be measured in end-stage renal disease patients presenting with skin necrosis. (C) 1998 by the National Kidney Foundation, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 11/07/20 alle ore 20:39:12