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Titolo:
TINNITUS AND EVENT-RELATED ACTIVITY OF THE AUDITORY-CORTEX
Autore:
HOKE ES; MUHLNICKEL W; ROSS B; HOKE M;
Indirizzi:
UNIV MUNSTER,INST EXPT AUDIOL,KARDINAL VON GALEN RING 10 D-48129 MUNSTER GERMANY HUMBOLDT UNIV,DEPT PSYCHOL BERLIN GERMANY
Titolo Testata:
Audiology & neuro-otology
fascicolo: 5, volume: 3, anno: 1998,
pagine: 300 - 331
SICI:
1420-3030(1998)3:5<300:TAEAOT>2.0.ZU;2-Z
Fonte:
ISI
Lingua:
ENG
Soggetto:
CONTINGENT NEGATIVE-VARIATION; EVOKED MAGNETIC-FIELDS; COCHLEAR HEARING-LOSS; NOISE-INDUCED TINNITUS; BRAIN-STEM RESPONSES; ATTENTIONAL DEMANDS; STIMULUS-INTENSITY; VARIATION CNV; POTENTIALS; ORGANIZATION;
Keywords:
TINNITUS; MAGNETOENCEPHALOGRAM; AUDITORY EVOKED POTENTIALS; AUDITORY EVOKED FIELDS; EVENT-RELATED POTENTIALS; EVENT-RELATED FIELDS; CONTINGENT NEGATIVE VARIATION; SPECTROTEMPORAL ANALYSIS; PLASTICITY; REORGANIZATION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
91
Recensione:
Indirizzi per estratti:
Citazione:
E.S. Hoke et al., "TINNITUS AND EVENT-RELATED ACTIVITY OF THE AUDITORY-CORTEX", Audiology & neuro-otology, 3(5), 1998, pp. 300-331

Abstract

A neuromagnetic study in tinnitus patients and normal-hearing controls was performed with a modified contingent negative variation (CNV) paradigm. While the warning stimulus S1 was a tone burst at an intensitywell above threshold, the imperative stimulus S2 was presented at a near threshold intensity because, in the majority of cases, the perceived loudness of tinnitus is very close to the threshold for a pure toneof the same frequency. Subjects had to respond to S2 by pressing a button until its offset was detected. In this case, instead of the usualsudden cut-off of the CNV after the perception of S2, a slow negativedeflection develops, the post-imperative negative variation (PINV). Its initial portion probably indicates the development of a second initial CNV because the subject had to attend also to the offset of S2. The neuromagnetic data were analysed both in the time domain and in the frequency domain (short-time spectral analysis of the classical EEG bands). The time domain waveform as well as the spectrotemporal patternsof the MEG bands exhibited deviations from the normal pattern in several tinnitus subgroups, depending on the characteristics of tinnitus (tonal vs, noisiform, monaural vs. binaural) and on the stimulation conditions (tinnitus side vs, non-tinnitus side).

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Documento generato il 19/01/20 alle ore 14:42:11