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Titolo:
OVARIAN MUCINOUS CYSTADENOCARCINOMA WITH MALIGNANT MURAL NODULES
Autore:
NAKAMURA E; SHIMIZU M; MIKAMI Y; KAWAI J; MANABE T;
Indirizzi:
KAWASAKI MED UNIV,DEPT PATHOL,577 MATSUSHIMA OKAYAMA 7010192 JAPAN
Titolo Testata:
Pathology international
fascicolo: 8, volume: 48, anno: 1998,
pagine: 645 - 648
SICI:
1320-5463(1998)48:8<645:OMCWMM>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
ANAPLASTIC CARCINOMA; TUMORS;
Keywords:
MUCINOUS CYSTADENOCARCINOMA; MURAL NODULES; OVARY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
15
Recensione:
Indirizzi per estratti:
Citazione:
E. Nakamura et al., "OVARIAN MUCINOUS CYSTADENOCARCINOMA WITH MALIGNANT MURAL NODULES", Pathology international, 48(8), 1998, pp. 645-648

Abstract

A case of ovarian mucinous cystadenocarcinoma with malignant mural nodules is reported. The patient was a 28-year-old Japanese female (gravida 0, para 0) with a 2 year history of increasing abdominal fullness and edema of the lower extremity. Physical examination showed a large mass in the abdomen. An abdominal ultrasound and computed tomography demonstrated a multilocular cyst with a solid component. Lymph node anddistant metastases were not found. These tests were followed by surgery. The resected right ovarian tumor measured 25 x 22 x 18cm. On cut sectioning, it was multilocular with multiple mural nodules. Microscopically, the cyst wall was lined with papillary infoldings of atypical mucinous epithelium (intestinal type). Nuclear stratification, cribriform and back-to-back glandular patterns and stromal invasion were observed. In addition, the solid area of the mural nodules showed spindle or polygonal cells with increased mitotic activity including atypical mitoses. Nuclear pleomorphism was marked. Necrosis and hemorrhage were also present. Reticulin stain showed these pleomorphic cell clusters circumscribed by reticulin fibers and these cells were immunoreactive for vimentin and p53.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/11/20 alle ore 17:43:51