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Titolo:
FURTHER STUDY ON THE CAROTID BAROREFLEX SYSTEM IN THE CARDIOVASCULAR DECONDITIONING INDUCED BY HEAD-DOWN TILT
Autore:
PANNIER B; SLAMA M; GUERIN A; MARTEL E; LONDON G; SAFAR M; CUCHE JL;
Indirizzi:
BROUSSAIS FAC MED,CATECHOLAMINE BIOL RES LAB,15 RUE ECOLE MED F-75270PARIS 06 FRANCE HOP MANHES,DEPT INTERNAL MED FLEURY MEROGIS FRANCE HOP BROUSSAIS,DEPT INTERNAL MED F-75674 PARIS FRANCE BROUSSAIS HD FAC MED,INSERM,U337 PARIS FRANCE
Titolo Testata:
Aviation, space, and environmental medicine
fascicolo: 9, volume: 69, anno: 1998,
pagine: 904 - 910
SICI:
0095-6562(1998)69:9<904:FSOTCB>2.0.ZU;2-3
Fonte:
ISI
Lingua:
ENG
Soggetto:
COLD PRESSOR TEST; BED REST; HYPERTENSIVE PATIENTS; HEALTHY-MEN; CATECHOLAMINES; DISTENSIBILITY; RESPONSES; ARTERIES; MUSCLE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
26
Recensione:
Indirizzi per estratti:
Citazione:
B. Pannier et al., "FURTHER STUDY ON THE CAROTID BAROREFLEX SYSTEM IN THE CARDIOVASCULAR DECONDITIONING INDUCED BY HEAD-DOWN TILT", Aviation, space, and environmental medicine, 69(9), 1998, pp. 904-910

Abstract

Hypothesis: The responses of the carotid baroreflex and of the peripheral sympathetic system to stimulations induced by either lower body negative pressure (LBNP -40 mmHg) or cold presser test were investigated in eight volunteers before and after 48 h in the -6 degrees head-down tilt (HDT). Methods: Geometry (diastolic diameter and pulsatile distention) and dynamics (cross-sectional compliance and tangential tension) of the bulb and the common carotid artery were investigated using ultrasonic devices, echotracking and aplanation tonometry. The activityof the sympathetic system was evaluated through measurements of plasma concentrations of catecholamines (CAs) and 3,4-dihydroxyphenyl glycol (DHPG). Results: During LBNP -40 mmHg, the pulsed tangential tensionwas decreased and the pressure amplification, induced by the reflexion of the pressure wave, was increased with no difference between before and after HDT. Since cross-sectional compliance and distensibility coefficient remained unchanged and the carotid contour of the waveform unaltered, it is concluded that the carotid reflexogenic area reads the same message during LBNP whether the cardiovascular system was deconditioned or not. Nonetheless, during LBNP after 48 h HDT, the heart rate accelerated faster and CAs and DHPG concentrations increased out ofproportion, suggesting that the peripheral sympathetic activity was more reactive after HDT than before. Finally, forearm vascular resistances were measured in response to cold presser test; they increased in the same proportion after HDT when compared with before. Conclusion: Results indicate that the carotid baroreflex and the peripheral sympathetic system were not deficient after 48 h HDT.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 06/04/20 alle ore 10:11:35