Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
CEREBRAL BLOOD-FLOW RELATIONSHIPS ASSOCIATED WITH A DIFFICULT TONE RECOGNITION TASK IN TRAINED NORMAL VOLUNTEERS
Autore:
HOLCOMB HH; MEDOFF DR; CAUDILL PJ; ZHAO Z; LAHTI AC; DANNALS RF; TAMMINGA CA;
Indirizzi:
MARYLAND PSYCHIAT RES CTR,POB 21247 BALTIMORE MD 21228 UNIV MARYLAND,DEPT PSYCHIAT COLLEGE PK MD 20742 JOHNS HOPKINS MED INST,DEPT RADIOL,DIV NUCL MED BALTIMORE MD 21205
Titolo Testata:
Cerebral cortex (New York, N.Y. 1991)
fascicolo: 6, volume: 8, anno: 1998,
pagine: 534 - 542
SICI:
1047-3211(1998)8:6<534:CBRAWA>2.0.ZU;2-B
Fonte:
ISI
Lingua:
ENG
Soggetto:
POSITRON EMISSION TOMOGRAPHY; STRUCTURED CLINICAL INTERVIEW; INFERIOR TEMPORAL NEURONS; WORKING-MEMORY TASKS; SHORT-TERM-MEMORY; AUDITORY-DISCRIMINATION; PREFRONTAL CORTEX; EPISODIC MEMORY; VERBAL MEMORY; CEREBELLAR;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
73
Recensione:
Indirizzi per estratti:
Citazione:
H.H. Holcomb et al., "CEREBRAL BLOOD-FLOW RELATIONSHIPS ASSOCIATED WITH A DIFFICULT TONE RECOGNITION TASK IN TRAINED NORMAL VOLUNTEERS", Cerebral cortex (New York, N.Y. 1991), 8(6), 1998, pp. 534-542

Abstract

Tone recognition is partially subserved by neural activity in the right frontal and primary auditory cortices. First we determined the brain areas associated with tone perception and recognition. This study then examined how regional cerebral blood flow (rCBF) in these and otherbrain regions correlates with the behavioral characteristics of a difficult tone recognition task. rCBF changes were assessed using (H2O)-O-15 Positron emission tomography. Subtraction procedures were used to localize significant change regions and correlational analyses were applied to determine how response times (RT) predicted rCBF patterns. Twelve trained normal volunteers were studied in three conditions: REST,sensory motor control (SMC) and decision (DEC). The SMC-REST contrastrevealed bilateral activation of primary auditory cortices, cerebellum and bilateral inferior frontal gyri. DEC-SMC produced significant clusters in the right middle and inferior frontal gyri, insula and claustrum; the anterior cingulate gyrus and supplementary motor area; the left insula/claustrum; and the left cerebellum. Correlational analyses,RT versus rCBF from DEC scans, showed a positive correlation in rightinferior and middle frontal cortex; rCBF in bilateral auditory cortices and cerebellum exhibited significant negative correlations with RT. These changes suggest that neural activity in the right frontal, superior temporal and cerebellar regions shifts hack and forth in magnitude depending on whether tone recognition RT is relatively fast or slow,during a difficult, accurate assessment.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/09/20 alle ore 09:37:03