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Titolo:
CHANGES IN CEREBRAL BLOOD-FLOW VELOCITIES ASSOCIATED WITH RADERMECKERCOMPLEXES IN A PATIENT WITH SUBACUTE SCLEROSING PANENCEPHALITIS - A CASE-REPORT
Autore:
DIEHL B; DEPPE M; RINGELSTEIN EB; STODIECK SRG;
Indirizzi:
CLEVELAND CLIN FDN,DEPT NEUROL,DESK S51,POST BOX 655,9500 EUCLID AVE CLEVELAND OH 44195 UNIV HOSP MUNSTER,DEPT NEUROL MUNSTER GERMANY
Titolo Testata:
Journal of epilepsy
fascicolo: 5, volume: 11, anno: 1998,
pagine: 270 - 275
SICI:
0896-6974(1998)11:5<270:CICBVA>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
INTERFERON;
Keywords:
SUBACUTE SCLEROSING PANENCEPHALITIS; RADERMECKER COMPLEXES; CEREBRAL BLOOD FLOW VELOCITIES;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
15
Recensione:
Indirizzi per estratti:
Citazione:
B. Diehl et al., "CHANGES IN CEREBRAL BLOOD-FLOW VELOCITIES ASSOCIATED WITH RADERMECKERCOMPLEXES IN A PATIENT WITH SUBACUTE SCLEROSING PANENCEPHALITIS - A CASE-REPORT", Journal of epilepsy, 11(5), 1998, pp. 270-275

Abstract

The electroencephalogram (EEG) in subacute sclerosing panencephalitis(SSPE) is characterized by generalized periodic high amplitude complexes recurring at intervals of 4-12 seconds (Radermecker complexes). Little is known about their genesis, although most authors favor a brainstem origin. We wished to study changes in cerebral perfusion associated with these complexes in order to better understand their pathophysiology. We present a 15-year old girl who was diagnosed to have SSPE with cognitive and intellectual decline. Radermecker complexes were first detected on EEG after an injection of midazolam. They occurred spontaneously 2 weeks later. We studied changes in cerebral blood flow velocities (CBFV) measured by transcranial Doppler (TCD) in both middle cerebral arteries (MCA) time-locked to the occurrence of the Radermecker complexes. Averaging 250 Radermecker complexes over five recording sessions demonstrated a biphasic signal with a decrease in CBFV by 5.8%, peaking at 0.7 seconds after the onset of the complexes, and a subsequent increase in CBFV by 3.7% peaking at 3 seconds after the be,inning of the complex. Changes in heart beat showed a similar course with an initial decrease and a subsequent increase in frequency. These similar temporal changes between CBFV and heart rate suggest that the pathophysiologic mechanisms of these complexes may also affect the balance of autonomic tone descending from brain to heart. (C) 1998 by ElsevierScience Inc. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/01/21 alle ore 03:42:43