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Titolo:
INFLUENCE OF TREATMENT DELAY ON INFARCT SIZE AND CLINICAL OUTCOME IN PATIENTS WITH ACUTE MYOCARDIAL-INFARCTION TREATED WITH PRIMARY ANGIOPLASTY
Autore:
LIEM AL; VANTHOF AWJ; HOORNTJE JCA; DEBOER MJ; SURYAPRANATA H; ZIJLSTRA F;
Indirizzi:
HOSP WEEZENLANDEN,DEPT CARDIOL,GROOT WEZENLAND 20 NL-8011 JW ZWOLLE NETHERLANDS HOSP WEEZENLANDEN,DEPT CARDIOL NL-8011 JW ZWOLLE NETHERLANDS
Titolo Testata:
Journal of the American College of Cardiology
fascicolo: 3, volume: 32, anno: 1998,
pagine: 629 - 633
SICI:
0735-1097(1998)32:3<629:IOTDOI>2.0.ZU;2-R
Fonte:
ISI
Lingua:
ENG
Soggetto:
PRIMARY CORONARY ANGIOPLASTY; LEFT-VENTRICULAR FUNCTION; THROMBOLYTIC THERAPY; INTRAVENOUS STREPTOKINASE; RANDOMIZED TRIAL; ARTERY PATENCY; SYMPTOM ONSET; RISK PATIENTS; REPERFUSION; MORTALITY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
21
Recensione:
Indirizzi per estratti:
Citazione:
A.L. Liem et al., "INFLUENCE OF TREATMENT DELAY ON INFARCT SIZE AND CLINICAL OUTCOME IN PATIENTS WITH ACUTE MYOCARDIAL-INFARCTION TREATED WITH PRIMARY ANGIOPLASTY", Journal of the American College of Cardiology, 32(3), 1998, pp. 629-633

Abstract

Objectives. The purpose of this analysis was to determine the influence of an additional treatment delay inherent in transfer to an angioplasty center for primary angioplasty of patients with acute myocardial infarction who are first admitted to hospitals without angioplasty facilities. Background. Several randomized trials have demonstrated the benefits of primary angioplasty in acute myocardial infarction. In recent years, increasing numbers of patients with myocardial infarction, initially admitted to hospitals without angioplasty facilities are transported to our hospital for primary angioplasty. However, the additional delay due to the transport may have a deleterious effect on infarctsize and clinical outcome. Methods. In a three-year period (December 1993 to November 1996), 207 consecutive patients who were transferred for primary angioplasty were analyzed in a matched comparison with non-transferred patients. Matching criteria were age, sex, infarct location, presentation delay and Killip class. Results. Patients who were transferred had an additional median delay of 43 min. This resulted in amore extensive enzymatic infarct size and a lower ejection fraction measured at 6 months. The rate of angioplasty success defined as TIMI grade 3 flow, and the 6-month mortality rate (7%) were comparable in both groups. Conclusions. The additional delay had a deleterious effect on myocardial salvage, reflected by a larger infarct size and a lower left ventricular function. However, the patency rate and 6-month clinical outcome were not affected by this delay. (J Am Coil Cardiol 1998;32:629-33) (C) 1998 by the American College of Cardiology.

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Documento generato il 30/09/20 alle ore 02:34:35