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Titolo:
HEPATITIS-G VIRUS-INFECTION IN HUMAN-IMMUNODEFICIENCY-VIRUS TYPE 1-INFECTED MOTHERS AND THEIR CHILDREN
Autore:
DEMARTINO M; AZZARI C; RESTI M; MORIONDO M; ROSSI ME; GALLI L; VIERUCCI A;
Indirizzi:
UNIV CHIETI,DEPT MED,DIV PEDIAT CHIETI ITALY UNIV FLORENCE,DEPT PEDIAT FLORENCE ITALY
Titolo Testata:
The Journal of infectious diseases
fascicolo: 3, volume: 178, anno: 1998,
pagine: 862 - 865
SICI:
0022-1899(1998)178:3<862:HVIHT1>2.0.ZU;2-C
Fonte:
ISI
Lingua:
ENG
Soggetto:
TRANSMISSION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
15
Recensione:
Indirizzi per estratti:
Citazione:
M. Demartino et al., "HEPATITIS-G VIRUS-INFECTION IN HUMAN-IMMUNODEFICIENCY-VIRUS TYPE 1-INFECTED MOTHERS AND THEIR CHILDREN", The Journal of infectious diseases, 178(3), 1998, pp. 862-865

Abstract

Hepatitis G virus (HGV) RNA and anti-E2 glycoprotein antibody (E2Ab) seroprevalence was studied in 58 human immunodeficiency virus type 1 (HIV-1)-infected mothers (34 injecting drug users [IDUs] and 24 with risky sexual behavior [RSB]) and their children (median age, 5 days; range, 1-27), Twelve women (20.6%) were RNA- and 20 (34.4%) E2Ab-positive. Seroprevalence was similar in 1:he IDU and RSB groups and high in RSB partners of IDU men. Five (41.6%) children of RNA-positive mothers were HGV-infected, at a median age of 5 days (range, 1-27), independentof maternal CD4 T lymphocyte numbers, mode of delivery, and HIV-1 transmission; no other child at risk became RNA-positive subsequently. NoHGV-infected child (follow-up, 16 months; range, 12-52) showed increased liver enzyme levels; 3 children cleared RNA and E2Ab-seroconvertedafter 10-48 months, Thus, in HIV-l-infected women, HGV infection is common and also sexually transmitted, and clearance may be impaired. Mother-to-child transmission is frequent and occurs antenatally; children remain long infected without evident disease.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 24/10/20 alle ore 13:28:07