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Titolo:
COMPARISON OF SKIN-PRICK TEST AND SPECIFIC SERUM IGE DETERMINATION FOR THE DIAGNOSIS OF LATEX ALLERGY
Autore:
BLANCO C; CARRILLO T; ORTEGA N; ALVAREZ M; DOMINGUEZ C; CASTILLO R;
Indirizzi:
HOSP NTRA,SECC ALERGIA,SRA PINO,C ANGEL GUIMERA 93 LAS PALMAS 35005 SPAIN HOSP NTRA,SERV ANALISIS CLIN LAS PALMAS 35005 SPAIN
Titolo Testata:
Clinical and experimental allergy
fascicolo: 8, volume: 28, anno: 1998,
pagine: 971 - 976
SICI:
0954-7894(1998)28:8<971:COSTAS>2.0.ZU;2-Z
Fonte:
ISI
Lingua:
ENG
Soggetto:
NATURAL-RUBBER LATEX; CONTACT URTICARIA; ANTIBODIES; PREVALENCE; HYPERSENSITIVITY; ASTHMA; IDENTIFICATION; ANAPHYLAXIS; BINDING; ALASTAT;
Keywords:
LATEX; DIAGNOSIS; SKIN-PRICK TEST; SPECIFIC IGE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
32
Recensione:
Indirizzi per estratti:
Citazione:
C. Blanco et al., "COMPARISON OF SKIN-PRICK TEST AND SPECIFIC SERUM IGE DETERMINATION FOR THE DIAGNOSIS OF LATEX ALLERGY", Clinical and experimental allergy, 28(8), 1998, pp. 971-976

Abstract

Background Latex IgE-mediated hypersensitivity has been recognized asan international health problem. However, there is poor information on the efficiency of the diagnostic methods available. Objective The purpose of this study was to specify the efficiency of several diagnostic methods for latex allergy. Methods We designed a prospective study involving 50 adult patients with latex allergy, as diagnosed by a suggestive clinical history and a positive skin-prick test (SPT) to a latexextract. One control group of 50 subjects paired for age, sex, total IgE levels and latex exposure, and another control group of 30 subjects with pollen allergy were used. A low-ammoniated natural-latex and several glove-latex extracts were elaborated. SPTs with these extracts, as well as with four different commercial-latex extracts were performed. Latex-specific serum IgE was determined by the CAP and the AlaSTAT methods. Results Diagnostic sensitivity was 98% for the natural-latex extract SPT, from 90% to 98% for the commercial-latex extract SPT, andfrom 64% to 96% for the glove-latex extract SPT. Diagnostic specificity of SPT was 100%, and no severe adverse reactions were observed during skin testing. With respect to the latex-specific serum IgE determinations, sensitivity was 86% for the CAP system and 84% for the AlaSTATassay, and specificity was dependent on the population considered. Conclusion SPT with natural latex extracts has shown a diagnostic efficiency close to 100%, significantly higher than that of latex-specific serum IgE determination.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/01/21 alle ore 08:53:02