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Titolo:
ARE THERE ANY BODY-FLUID MARKERS OF BRAIN ATROPHY IN MULTIPLE-SCLEROSIS
Autore:
GIOVANNONI G; GREEN AJE; THOMPSON EJ;
Indirizzi:
INST NEUROL,DEPT CLIN NEUROL,QUEEN SQ LONDON WC1N 3BG ENGLAND INST NEUROL,DEPT NEUROCHEM LONDON WC1N 3BG ENGLAND
Titolo Testata:
Multiple sclerosis
fascicolo: 3, volume: 4, anno: 1998,
pagine: 138 - 142
SICI:
1352-4585(1998)4:3<138:ATABMO>2.0.ZU;2-T
Fonte:
ISI
Lingua:
ENG
Soggetto:
NEURON-SPECIFIC ENOLASE; MYELIN BASIC-PROTEIN; FIBRILLARY ACIDIC PROTEIN; CEREBROSPINAL-FLUID; DISEASE PROGRESSION; SPINAL-CORD; NEUROLOGICAL DISORDERS; HYPOINTENSE LESIONS; NERVOUS-SYSTEM; S-100B PROTEIN;
Keywords:
MULTIPLE SCLEROSIS; URINE; NEOPTERIN;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
40
Recensione:
Indirizzi per estratti:
Citazione:
G. Giovannoni et al., "ARE THERE ANY BODY-FLUID MARKERS OF BRAIN ATROPHY IN MULTIPLE-SCLEROSIS", Multiple sclerosis, 4(3), 1998, pp. 138-142

Abstract

The weak correlation between inflammatory activity and disease Progression in patients with multiple sclerosis has shifted the emphasis from inflammatory monitoring to the investigation of the pathological processes of demyelination, axonal loss, and gliosis. New magnetic resonance imaging (MRI) techniques that have been developed to measure theseprocesses appear very promising. This paper will briefly discuss potential body fluid markers of axonal loss, gliosis and demyelination, asthe Pathological substrates of brain atrophy, their function and the principles behind their future study in patients with multiple sclerosis.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/01/20 alle ore 06:33:25