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Titolo:
NEW INDIRECT PATHWAYS SUBSERVING THE PUPILLARY LIGHT REFLEX - PROJECTIONS OF THE ACCESSORY OCULOMOTOR NUCLEI AND THE PERIAQUEDUCTAL GRAY TOTHE EDINGER-WESTPHAL NUCLEUS AND THE THORACIC SPINAL-CORD IN RATS
Autore:
KLOOSTER J; VRENSEN GFJM;
Indirizzi:
NETHERLANDS OPHTHALM RES INST,DEPT MORPHOL,POB 12141 NL-1100 AC AMSTERDAM NETHERLANDS
Titolo Testata:
Anatomy and embryology
fascicolo: 2, volume: 198, anno: 1998,
pagine: 123 - 132
SICI:
0340-2061(1998)198:2<123:NIPSTP>2.0.ZU;2-Q
Fonte:
ISI
Lingua:
ENG
Soggetto:
OLIVARY PRETECTAL NUCLEUS; ALBINO-RAT; NEURONS; CAT; LUMINANCE; DETECTORS; MONKEY; SYSTEM;
Keywords:
PARASYMPATHETIC; SYMPATHETIC; PUPILLARY LIGHT REFLEX; LID CLOSURE REFLEX; PHASEOLUS VULGARIS LEUKOAGGLUTININ; INTERSTITIAL NUCLEUS OF CAJAL; NUCLEUS OF THE POSTERIOR COMMISSURE; NUCLEUS OF DARKSCHEWITSCH; PERIAQUEDUCTAL GRAY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
32
Recensione:
Indirizzi per estratti:
Citazione:
J. Klooster e G.F.J.M. Vrensen, "NEW INDIRECT PATHWAYS SUBSERVING THE PUPILLARY LIGHT REFLEX - PROJECTIONS OF THE ACCESSORY OCULOMOTOR NUCLEI AND THE PERIAQUEDUCTAL GRAY TOTHE EDINGER-WESTPHAL NUCLEUS AND THE THORACIC SPINAL-CORD IN RATS", Anatomy and embryology, 198(2), 1998, pp. 123-132

Abstract

The pupillary light reflex (PLR) is under the control of retinal ganglion cells projecting to the olivary pretectal nucleus (OPN). The OPN has a major projection to the Edinger-Westphal (EW) nucleus, which exerts its parasympathetic action on the iris musculature via the ciliaryganglion. The accessory oculomotor nuclei (AON) and the periaqueductal gray (PAG) receive input from the OPN and influence the PLR. The present study in rats aimed to elucidate the possible projections from the AON and FAG to the EW nucleus. The anterograde tracer Phaseolus vulgaris leucoagglutinin (PHA-L) was iontophoretically injected into the interstitial nucleus of Cajal (INC), the nucleus of the posterior commissure (NPC), the nucleus of Darkschewitsch (ND) and the rostral part of the FAG. The projections were studied at the light and electron microscopic level. The INC, NPC and ND have small projections to the EW nucleus, whereas the rostral part of the FAG densely projects to the EW nucleus. Without exception INC, NPC, ND and FAG varicosities are presynaptic to dendritic profiles in the EW nucleus and contain electron dense mitochondria, round vesicles and make asymmetric synaptic contacts. In addition the ND and FAG project to the thoracic level of the spinal cord. The fibres are presynaptic to dendritic profiles and contain electron dense mitochondria, round vesicles and make asymmetric synaptic contacts. The present observations allow the conclusion that the parasympathetic preganglionic neurons in the EW nucleus are not only controlled by the OPN-EW pathway but also by indirect pathways running via the AON and FAG. Moreover light-sensitive information is also transferred via an OPN-PAG-spinal cord pathway to the sympathetic superior cervical ganglion (SCG) that innervates the iris, suggesting that the FAG may have an integrative function in the sympathetic and parasympathetic control of the PLR.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/04/20 alle ore 12:08:41