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Titolo:
EVOLUTION OF HIV ANTIBODY TESTING
Autore:
ATAMANONAL Y; BIRON F; VERRIER B;
Indirizzi:
ECOLE NORMALE SUPER LYON,CNRS,UNITE MIXTE BIOMERIEUX,46 ALLEE ITALIE F-69364 LYON 07 FRANCE
Titolo Testata:
Medecine et maladies infectieuses
fascicolo: 6-7, volume: 28, anno: 1998,
pagine: 496 - 504
SICI:
0399-077X(1998)28:6-7<496:EOHAT>2.0.ZU;2-C
Fonte:
ISI
Lingua:
FRE
Soggetto:
HUMAN-IMMUNODEFICIENCY-VIRUS; SUBTYPE-O; SYNTHETIC PEPTIDE; HTLV-III; TYPE-1; ASSAY; SENSITIVITY; IMMUNOASSAY; INFECTION; SALIVA;
Keywords:
ANTI-HIV ANTIBODIES; ELISA; SALIVA TESTING; URINE TESTING; HIV HOME TEST;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
60
Recensione:
Indirizzi per estratti:
Citazione:
Y. Atamanonal et al., "EVOLUTION OF HIV ANTIBODY TESTING", Medecine et maladies infectieuses, 28(6-7), 1998, pp. 496-504

Abstract

The HIV screening ELISA detects anti-HIV1 and anti-HIV2 antibodies inblood samples. This is the most commonly used method for the detection of infection in blood donors or individuals at risk. Thanks to progress in technology, recombinant or synthetic peptide based antigens were incorporated in these assays to address specificity problems. The sensitivity was improved by the ability to detect all immunoglobulin classes. The high genetic variability of HIV and especially that of the group O is another problem to be dealt with. New kinds of high sensitivity ELISA can detect antibodies in non-blood samples such as saliva orurine. Simple, rapid, non-instrumental HIV tests are used in additionto ELISA. These simple assays, combined with non-invasive sample collection have made HIV home tests possible.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/11/20 alle ore 09:58:08