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Titolo:
GASTRIC MECHANOSENSORY AND LOWER ESOPHAGEAL SPHINCTER FUNCTION IN RUMINATION SYNDROME
Autore:
THUMSHIRN M; CAMILLERI M; HANSON RB; WILLIAMS DE; SCHEI AJ; KAMMER PP;
Indirizzi:
MAYO CLIN & MAYO FDN,GASTROENTEROL RES UNIT,GI UNIT ALFRED 2-435,200 1ST ST SW ROCHESTER MN 55905 MAYO CLIN & MAYO FDN,GASTROENTEROL RES UNIT ROCHESTER MN 55905 MAYO CLIN & MAYO FDN,SECT BEHAV MED ROCHESTER MN 55905
Titolo Testata:
American journal of physiology: Gastrointestinal and liver physiology
fascicolo: 2, volume: 38, anno: 1998,
pagine: 314 - 321
SICI:
0193-1857(1998)38:2<314:GMALES>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Soggetto:
COLD PRESSOR TEST; BULIMIA-NERVOSA; ANOREXIA-NERVOSA; ADULT PATIENT; TONE; METABOLISM; STOMACH; MOTOR;
Keywords:
LOWER ESOPHAGEAL SPHINCTER RELAXATION; GASTRIC TONE; MOTILITY; SENSATION; BAROSTAT; DENT SLEEVE; ACCOMMODATION; GLUCAGON; COLD STRESS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
40
Recensione:
Indirizzi per estratti:
Citazione:
M. Thumshirn et al., "GASTRIC MECHANOSENSORY AND LOWER ESOPHAGEAL SPHINCTER FUNCTION IN RUMINATION SYNDROME", American journal of physiology: Gastrointestinal and liver physiology, 38(2), 1998, pp. 314-321

Abstract

Our hypothesis was that rumination syndrome is associated with gastric sensory and motor dysfunction. We studied gastric and somatic sensitivity, reflex relaxation of the lower esophageal sphincter (LES), and gastric compliance and accommodation postprandially and postglucagon. A baro-statically controlled gastric bag and esophageal manometry wereused to compare gastric sensorimotor functions and LES relaxation to gastric distension in 12 patients with rumination syndrome and 12 controls. During bag distensions, patients had greater nausea, bloating, and aggregate score, but not pain, compared with controls (P < 0.05). At 4 and 8 mmHg gastric distension, LES tone reduction was greater in patients than in controls (P < 0.05). Gastric compliance, accommodationto a standard meal, and response to glucagon were not different in patients and controls; however 6 of 12 patients had no gastric accommodation; the latter patients had significantly greater pain perception during distension (P < 0.05) but normal somatic sensitivity compared with healthy controls. Rumination syndrome is characterized by higher gastric sensitivity and LES relaxation during gastric distension. A subgroup of patients also had absent postprandial accommodation.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/04/20 alle ore 09:46:22