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Titolo:
EVIDENCE FOR A NOVEL BURSTING MECHANISM IN RODENT TRIGEMINAL NEURONS
Autore:
DELNEGRO CA; HSIAO CF; CHANDLER SH; GARFINKEL A;
Indirizzi:
UNIV CALIF LOS ANGELES,DEPT PHYSIOL SCI,2851 SLICHTER HALL LOS ANGELES CA 90095 UNIV CALIF LOS ANGELES,DEPT PHYSIOL SCI LOS ANGELES CA 90095 UNIV CALIF LOS ANGELES,DEPT MED CARDIOL LOS ANGELES CA 90095
Titolo Testata:
Biophysical journal
fascicolo: 1, volume: 75, anno: 1998,
pagine: 174 - 182
SICI:
0006-3495(1998)75:1<174:EFANBM>2.0.ZU;2-6
Fonte:
ISI
Lingua:
ENG
Soggetto:
MODEL; OSCILLATIONS; DISSECTION; SLOW;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
31
Recensione:
Indirizzi per estratti:
Citazione:
C.A. Delnegro et al., "EVIDENCE FOR A NOVEL BURSTING MECHANISM IN RODENT TRIGEMINAL NEURONS", Biophysical journal, 75(1), 1998, pp. 174-182

Abstract

We investigated bursting behavior in rodent trigeminal neurons. The essential mechanisms operating in the biological systems were determined based on testable predictions of mathematical models. Bursting activity in trigeminal motoneurons is consistent with a traditional mechanism employing a region of negative slope resistance in the steady-statecurrent-voltage relationship (Smith, T. G. 1975. Nature. 253:450-452). However, the bursting dynamics of trigeminal interneurons is inconsistent with the traditional mechanisms, and is far more effectively explained by a new model of bursting that exploits the unique stability properties associated with spike threshold (Baer, S. M., T. Emeux, and J. Rinzel. 1989. SIAM J. Appl. Math. 49:55-71).

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Documento generato il 05/12/20 alle ore 01:10:53