Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
COMBINED VERSUS SEQUENTIAL HORMONAL REPLACEMENT THERAPY - A DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY ON QUALITY OF LIFE-RELATED OUTCOME MEASURES
Autore:
BECH P; MUNKJENSEN N; OBEL EB; ULRICH LG; EIKEN P; NIELSEN SP;
Indirizzi:
FREDERIKSBORG CENT CTY HOSP,INST PSYCHIAT DK-3400 HILLEROD DENMARK FREDERIKSBORG CENT CTY HOSP,DEPT CLIN PHYSIOL DK-3400 HILLEROD DENMARK HORSHOLM HOSP,DEPT GYNAECOL HORSHOLM DENMARK NOVO NORDISK AS DK-2880 BAGSVAERD DENMARK
Titolo Testata:
Psychotherapy and psychosomatics
fascicolo: 4-5, volume: 67, anno: 1998,
pagine: 259 - 265
SICI:
0033-3190(1998)67:4-5<259:CVSHRT>2.0.ZU;2-7
Fonte:
ISI
Lingua:
ENG
Soggetto:
OF-LIFE; POSTMENOPAUSAL WOMEN; MENOPAUSAL SYMPTOMS; TRIAL;
Keywords:
HORMONAL REPLACEMENT THERAPY; ESTRADIOL; NORETHISTERONE ACETATE; QUALITY OF LIFE; MENOPAUSE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Physical, Chemical & Earth Sciences
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
29
Recensione:
Indirizzi per estratti:
Citazione:
P. Bech et al., "COMBINED VERSUS SEQUENTIAL HORMONAL REPLACEMENT THERAPY - A DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY ON QUALITY OF LIFE-RELATED OUTCOME MEASURES", Psychotherapy and psychosomatics, 67(4-5), 1998, pp. 259-265

Abstract

Background: To compare combined and sequential hormonal replacement therapies to each other as well as placebo in patients suffering from the postmenopausal syndrome. Clinical outcomes were measured concerningboth the specific postmenopausal symptoms (using the Kupperman scale)and health or well-being dimensions (using subscales of the General Health Questionnaire and specific depression and anxiety scales). Methods: A prospective randomized double-blind study over 12 months of 105 normal early postmenopausal women in the setting of a general hospital. Results: Both hormone replacement therapies were superior to placeboon the Kupperman scale (sweating, hot flushing, myalgia and vertigo). The psychic symptoms on the Kupperman scale were psychometrically invalid. However, psychic symptoms as measured by the Beck Depression Inventory and the General Health Questionnaire were significantly improved by the hormonal replacement therapies. No differences were observed when combined therapy was compared to sequential therapy. Conclusion: One-year treatment with hormonal replacement therapy is superior to placebo in measuring the somatic and psychic symptoms of the menopausal syndrome. No differences were found in this respect be:tween combined and sequential replacement therapy.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 24/11/20 alle ore 14:11:29