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Titolo:
ARTERIAL RESPONSE DURING COLD PRESSOR TEST IN BORDERLINE HYPERTENSION
Autore:
LAFLECHE AB; PANNIER BM; LALOUX B; SAFAR ME;
Indirizzi:
HOP BROUSSAIS,DEPT INTERNAL MED,96 RUE DIDOT F-75014 PARIS FRANCE HOP BROUSSAIS,DEPT INTERNAL MED F-75014 PARIS FRANCE HOP BROUSSAIS,INSERM,U337 F-75014 PARIS FRANCE MANHES HOSP F-91700 FLEURY MEROGIS FRANCE
Titolo Testata:
American journal of physiology. Heart and circulatory physiology
fascicolo: 2, volume: 44, anno: 1998,
pagine: 409 - 415
SICI:
0363-6135(1998)44:2<409:ARDCPT>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
SYMPATHETIC-NERVE ACTIVITY; WAVE REFLECTIONS; BLOOD-PRESSURE; CHRONIC UREMIA; SHORT-TERM; DISTENSIBILITY; HEMODYNAMICS; HUMANS;
Keywords:
PULSATILE ARTERIAL HEMODYNAMICS; WAVE REFLECTION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
37
Recensione:
Indirizzi per estratti:
Citazione:
A.B. Lafleche et al., "ARTERIAL RESPONSE DURING COLD PRESSOR TEST IN BORDERLINE HYPERTENSION", American journal of physiology. Heart and circulatory physiology, 44(2), 1998, pp. 409-415

Abstract

We observed previously that sympathetic activation produced by lower body negative pressure increases pulse-pressure amplification with little change in mean pressure. Whether the cold presser test (CPT) mightproduce a similar hemodynamic pattern has been ignored. Ten subjects with borderline hypertension and ten age- and sex-matched normotensivecontrols were compared to investigate carotid-brachial pulse-pressureamplification (aplanation tonometry) and changes in brachial and carotid distensibility (echotracking technique) before and during CPT. Themaneuver markedly increased blood pressure without a change in heart rate. Pulse-pressure amplification tended to disappear as a consequence of a higher increase in carotid than in brachial pulse pressure, dueto an earlier return of wave reflections at the carotid site. CPT caused a significant decrease in carotid and brachial distensibility. Both results were more pronounced in controls than in borderline hypertensives. Thus CPT reduces pulse-pressure amplification. In humans, this change may greatly influence the calculation of arterial distensibility, although this point is usually minimized in animal experiments. Furthermore, in young subjects, sympathetic stimulus may induce differentarterial responses, depending on the mechanism involved: reflex or global nonspecific stimulus.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/11/20 alle ore 20:01:55