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Titolo:
RELATIONSHIP BETWEEN GRADE OF INTRADUCTAL COMPONENT OF BREAST-CANCER WITHIN MAIN TUMOR AND EXTENT OF INTRADUCTAL SPREAD IN SURROUNDING TISSUE
Autore:
KUROSUMI M; SUEMASU K; TABEI T; KUWASHIMA Y; TAKEO T; KUSAWAKE T; HIGASHI Y;
Indirizzi:
SAITAMA CANC CTR,DEPT CLIN PATHOL,818 KOMURO INA SAITAMA 3620806 JAPAN SAITAMA CANC CTR,CLIN BREAST SURG INA SAITAMA 3620806 JAPAN SAITAMA CANC CTR,CLIN ENDOCRINE DIS INA SAITAMA 3620806 JAPAN
Titolo Testata:
Anticancer research
fascicolo: 4B, volume: 18, anno: 1998,
pagine: 2869 - 2873
SICI:
0250-7005(1998)18:4B<2869:RBGOIC>2.0.ZU;2-7
Fonte:
ISI
Lingua:
ENG
Soggetto:
LOCAL RECURRENCE; CONSERVING SURGERY; STAGE-I; QUADRANTECTOMY; IRRADIATION; LUMPECTOMY; CARCINOMA; THERAPY;
Keywords:
BREAST NEOPLASM; BREAST CONSERVING SURGERY; INTRADUCTAL COMPONENT; IMMUNOHISTOCHEMISTRY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
14
Recensione:
Indirizzi per estratti:
Citazione:
M. Kurosumi et al., "RELATIONSHIP BETWEEN GRADE OF INTRADUCTAL COMPONENT OF BREAST-CANCER WITHIN MAIN TUMOR AND EXTENT OF INTRADUCTAL SPREAD IN SURROUNDING TISSUE", Anticancer research, 18(4B), 1998, pp. 2869-2873

Abstract

Ninety-three specimens obtained by quadrantectomy of invasive ductal carcinoma of the breast were examined to evaluate the correlation between the grade of the intraductal component within the tumor and the extent of intraductal spread in the surrounding tissue. We used immunohistochemistry of a-smooth muscle actin to visualize the contour of intraductal components. The grade of the intraductal component within the tumor was classified into 4 groups (td0 to td3) by counting number of intraductal components; the extent of intraductal spread in the surrounding tissue was also divided into 4 groups (sd0 to sd3) according distance from the tumor margin. Fifty-eight (89.2%) of 65 cases with low-grade td were low-grade sd, and 17 (60.7%) cases of high-grade td werehigh-grade of sd The grade of the intraductal component correlated with the extent of intraductal spread in the surrounding tissue, significantly (p<0.001, Spearman rank correlation test). From these results, we belive that investigation of intraductal components within the tumor is useful for estimating the extent of intraductal spread in the surrounding tissue, and excision specimens from diagnostic lumpectomy should be examined for the extent of the intraductal component, the results being important in estimating the risk of local recurrence.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 06/04/20 alle ore 21:40:42