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Titolo:
SIALIC-ACID, TRANSKETOLASE AND NA-ARTHRITIS(, K+, ATPASE IN PATIENTS WITH RHEUMATOID)
Autore:
KIZILTUNC A; COGALGIL S; UGUR M; AVCI B; AKCAY F;
Indirizzi:
ATATURK UNIV,SCH MED,DEPT BIOCHEM TR-25240 ERZURUM TURKEY ATATURK UNIV,SCH MED,DEPT PHYS MED & REHABIL TR-25240 ERZURUM TURKEY
Titolo Testata:
CLINICAL CHEMISTRY AND LABORATORY MEDICINE
fascicolo: 5, volume: 36, anno: 1998,
pagine: 289 - 293
SICI:
1434-6621(1998)36:5<289:STANKA>2.0.ZU;2-G
Fonte:
ISI
Lingua:
ENG
Soggetto:
RED-BLOOD-CELLS; SERUM; ABNORMALITY; THIAMINE; DISEASE; HYPERTENSION; TRANSPORT; CANCER;
Keywords:
SIALIC ACID; TRANSKETOLASE; RHEUMATOID ARTHRITIS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
38
Recensione:
Indirizzi per estratti:
Citazione:
A. Kiziltunc et al., "SIALIC-ACID, TRANSKETOLASE AND NA-ARTHRITIS(, K+, ATPASE IN PATIENTS WITH RHEUMATOID)", CLINICAL CHEMISTRY AND LABORATORY MEDICINE, 36(5), 1998, pp. 289-293

Abstract

We studied transketolase activity of red blood cell hemolysates, and Na+, K+, ATPase activity and sialic acid concentration in red blood cell membranes from 52 patients with rheumatoid arthritis and 24 controlsubjects. Decreased red blood cell membrane Na+, K+, ATPase activity and sialic acid concentration and decreased transketolase in red bloodcell hemolysates were observed in rheumatoid arthritis patients compared with control subjects (p<0.001). Erythrocyte sedimentation rate and C-reactive protein values were increased in rheumatoid arthritis patients compared with control subjects (p<0.0001). Significant correlations between sialic acid and Na+, K+, ATPase (r=0.65, p<0.001) and between sialic acid and transketolase (r=0.58, p<0.001) were observed. Erythrocyte sedimentation rate and C-reactive protein levels did not correlate with Na+, K+, ATPase activity or with sialic acid or transketolase in rheumatoid arthritis patients. These data show that decreases inNa+, K+, ATPase, and transketolase activities and sialic acid concentration are present in rheumatoid arthritis patients, and that the decrease in Na+, K+, ATPase and transketolase activities in rheumatoid arthritis might be due to decreased sialic acid.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 07/07/20 alle ore 11:27:48