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Titolo:
ALEUKEMIC GRANULOMATOUS LEUKEMIA-CUTIS
Autore:
TOMASINI C; QUAGLINO P; NOVELLI M; FIERRO MT;
Indirizzi:
UNIV TURIN,SECT DERMATOL 1,DEPT MED & SURG SPECIALTIES,VIA CHERASCO 23 I-10126 TURIN ITALY
Titolo Testata:
The American journal of dermatopathology
fascicolo: 4, volume: 20, anno: 1998,
pagine: 417 - 421
SICI:
0193-1091(1998)20:4<417:AGL>2.0.ZU;2-Z
Fonte:
ISI
Lingua:
ENG
Soggetto:
ACUTE MYELOMONOCYTIC LEUKEMIA; FLOW CYTOMETRIC ANALYSIS; T-CELL LYMPHOMAS; MYELOGENOUS LEUKEMIA; CLASSIFICATION; PROPOSAL; SKIN;
Keywords:
ALEUKEMIC LEUKEMIA CUTIS; GRANULOMA; HISTOPATHOLOGY; IMMUNOPHENOTYPE; MYELOMONOCYTIC LEUKEMIA;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
25
Recensione:
Indirizzi per estratti:
Citazione:
C. Tomasini et al., "ALEUKEMIC GRANULOMATOUS LEUKEMIA-CUTIS", The American journal of dermatopathology, 20(4), 1998, pp. 417-421

Abstract

Aleukemic leukemia cutis is a rare condition characterized by the infiltration of the skin by leukemic cells before their appearance in theperipheral blood. The authors report a case of aleukemic leukemia cutis in a 30-year-old seemingly healthy man who presented with multiple skin papulonodular lesions and lack of peripheral blood involvement. Histopathologically, the skin infiltrates showed prominent granulomatous features that masked the underlying malignant process. Immunophenotypic studies of skin and bone marrow infiltrates revealed the myelomonocytic lineage of the atypical cells, consistent with M4 acute myelomonocytic leukemia. The authors emphasize the value of immunohistochemical studies in diagnosing a cutaneous atypical infiltrate and discuss problems of histopathologic differential diagnosis.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/11/20 alle ore 16:22:36