Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
SEIZURE ACTIVITY INDUCES PIM-1 EXPRESSION IN BRAIN
Autore:
FELDMAN JD; VICIAN L; CRISPINO M; TOCCO G; BAUDRY M; HERSCHMAN HR;
Indirizzi:
UNIV CALIF LOS ANGELES,INST MOL BIOL,CTR HLTH SCI,611 CIRCLE DR E LOSANGELES CA 90095 UNIV CALIF LOS ANGELES,INST MOL BIOL,CTR HLTH SCI LOS ANGELES CA 90095 UNIV CALIF LOS ANGELES,CTR HLTH SCI,DEPT PEDIAT LOS ANGELES CA 90024 UNIV CALIF LOS ANGELES,CTR HLTH SCI,DEPT BIOL CHEM LOS ANGELES CA 90024 UNIV CALIF LOS ANGELES,CTR HLTH SCI,DEPT MOL & MED PHARMACOL LOS ANGELES CA 90024 UNIV SO CALIF,NEUROSCI PROGRAM LOS ANGELES CA 90089
Titolo Testata:
Journal of neuroscience research
fascicolo: 4, volume: 53, anno: 1998,
pagine: 502 - 509
SICI:
0360-4012(1998)53:4<502:SAIPEI>2.0.ZU;2-K
Fonte:
ISI
Lingua:
ENG
Soggetto:
REPRESENTATIONAL DIFFERENCE ANALYSIS; TEMPORAL-LOBE EPILEPSY; LONG-TERM POTENTIATION; IMMEDIATE-EARLY GENE; ADULT-RAT BRAIN; KAINIC ACID; MESSENGER-RNA; SYNAPTIC ACTIVITY; TRANSGENIC MICE; PROTEIN;
Keywords:
KAINIC ACID; PC12 CELLS; PROTEIN KINASES; REPRESENTATIONAL DIFFERENCE ANALYSIS; DEPOLARIZATION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
41
Recensione:
Indirizzi per estratti:
Citazione:
J.D. Feldman et al., "SEIZURE ACTIVITY INDUCES PIM-1 EXPRESSION IN BRAIN", Journal of neuroscience research, 53(4), 1998, pp. 502-509

Abstract

We recently identified KID-1, a previously undescribed protein kinaseinduced by depolarization in PC12 cells and brain (Feldman ct al,, 1998), KID-1 shares a high degree of sequence homology with RIM-I, a proto-oncogene previously reported to be expressed in hematopoietic and germ cells, We examined PIM-I expression in stimulated PC12 cells, brains of kainic acid-treated rats, and a number of tissues from untreatedrats, We now report that forskolin, but not depolarization or growth factors, induces PIM-I expression in PC12 cells, PIM-1 is an immediateearly gene induced in response to forskolin stimulation. We detect PIM-I mRNA in a number of unstimulated tissues and at low levels in unstimulated brain, Systemic kainic acid administration to adult rats induces PIM-I expression in the dentate gyrus region of the hippocampus. (C) 1998 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/01/21 alle ore 10:05:50