Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
ANXIOLYTIC AND MEMORY IMPROVING EFFECTS OF MOCLOBEMIDE
Autore:
NOWAKOWSKA E; CHODERA A; KUS K; RYBAKOWSKI J;
Indirizzi:
KAROL MARCINKOWSKI UNIV MED SCI,DEPT PHARMACOL,SCH MED,10 FEDRY STQ PL-61701 POZNAN POLAND KAROL MARCINKOWSKI UNIV MED SCI,DEPT ADULT PSYCHIAT,SCH MED PL-61701 POZNAN POLAND
Titolo Testata:
Arzneimittel-Forschung
fascicolo: 6, volume: 48, anno: 1998,
pagine: 625 - 628
SICI:
0004-4172(1998)48:6<625:AAMIEO>2.0.ZU;2-7
Fonte:
ISI
Lingua:
ENG
Soggetto:
COGNITIVE FUNCTIONS; ELDERLY PATIENTS; BENZODIAZEPINES; TRIAL;
Keywords:
ANTIDEPRESSANTS; CAS 71320-77-9; MOCLOBEMIDE; MONOAMINE A OXIDASE INHIBITOR; RO 11-1163, ANXIOLYTIC AND MEMORY IMPROVING EFFECTS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
22
Recensione:
Indirizzi per estratti:
Citazione:
E. Nowakowska et al., "ANXIOLYTIC AND MEMORY IMPROVING EFFECTS OF MOCLOBEMIDE", Arzneimittel-Forschung, 48(6), 1998, pp. 625-628

Abstract

The anxiolytic and memory enhancing effects of moclobemide (p-chloro-N-(2-morphinoethyl)benzamide, CAS 71320-77-9, Ro 11-1163), a reversible and selective monoamine A oxidase inhibitor, were investigated in rats. It was found that the drug had an anxiolytic activity lasting in chronic experiments over 2 weeks. The used dose of the drug did not change animal locomotion in activity cages. In memory experiments (food finding time in maze), moclobemide exerted a favorable effect only after a single administration. In rats with scopolamine-impaired memory, moclobemide attenuated the effects of scopolamine in single and chronicexperiments.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/01/20 alle ore 19:07:45